Innate Lymphoid Cells in the Induction of Obesity.

Adipose Tissue, White / cytology Animals DNA-Binding Proteins / genetics Diet, High-Fat Gastrointestinal Microbiome / genetics Immunity, Innate Interleukin Receptor Common gamma Subunit / genetics Interleukin-2 / metabolism Intestine, Small / cytology Killer Cells, Natural / immunology Lymphocytes / cytology Macrophages / metabolism Mice Mice, Inbred C57BL Mice, Knockout Obesity / immunology
ILC2 ILC3 common gamma chain high-fat diet innate lymphoid cells interleukin-2 obesity small intestine white adipose tissue γ(c)

Journal

Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691

Informations de publication

Date de publication:
02 07 2019
Historique:
received: 24 06 2017
revised: 16 04 2019
accepted: 04 06 2019
entrez: 4 7 2019
pubmed: 4 7 2019
medline: 28 8 2020
Statut: ppublish

Résumé

Complex interactions between immune cells are an important component in the induction of obesity. Here, we show that Il2rg

Identifiants

DOI: 10.1016/j.celrep.2019.06.016 PMID: 31269440
pubmed: 31269440
pii: S2211-1247(19)30782-X
doi: 10.1016/j.celrep.2019.06.016
pii:
doi:

Substances chimiques

DNA-Binding Proteins 0
Il2rg protein, mouse 0
Interleukin Receptor Common gamma Subunit 0
Interleukin-2 0
Rag2 protein, mouse 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

202-217.e7

Informations de copyright

Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.

Auteurs

Takaharu Sasaki (T)

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.

Kazuyo Moro (K)

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan; Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine, Osaka, Japan. Electronic address: kazuyo.moro@riken.jp.

Tetsuya Kubota (T)

Laboratory for Metabolic Homeostasis, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.

Naoto Kubota (N)

Laboratory for Metabolic Homeostasis, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.

Tamotsu Kato (T)

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan.

Hiroshi Ohno (H)

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan; Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kanagawa, Japan.

Susumu Nakae (S)

Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Hirohisa Saito (H)

Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.

Shigeo Koyasu (S)

Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Deparment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan. Electronic address: shigeo.koyasu@riken.jp.

Articles similaires

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Classifications MeSH

questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux blanc › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Eucaryotes › Animaux › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de liaison à l'ADN › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Alimentation riche en graisse › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité innée › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux interleukines › Récepteurs à l'interleukine-21 › Sous-unité gamma commune aux récepteurs des interleukines › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Lymphokines › Interleukine-2 › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › Intestin grêle › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Cellules tueuses naturelles › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Innate Lymphoid Cells in the Induction of Obesity.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Innate Lymphoid Cells in the Induction of Obesity.