Cervical cancer screening rate differs by HPV vaccination status: An interim analysis.
Adult
Early Detection of Cancer
/ statistics & numerical data
Female
Humans
Incidence
Japan
Mass Screening
/ statistics & numerical data
Papillomaviridae
/ immunology
Papillomavirus Infections
/ immunology
Papillomavirus Vaccines
/ immunology
Surveys and Questionnaires
Uterine Cervical Neoplasms
/ diagnosis
Vaccination
/ statistics & numerical data
Young Adult
Cervical cancer
HPV vaccine
Screening rate
Vaccination status
Journal
Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899
Informations de publication
Date de publication:
26 07 2019
26 07 2019
Historique:
received:
22
01
2019
revised:
27
05
2019
accepted:
19
06
2019
pubmed:
6
7
2019
medline:
17
9
2020
entrez:
6
7
2019
Statut:
ppublish
Résumé
The incidence of cervical cancer has been increasing, especially in younger generation, in Japan. The females born between 1994 and 1999, who achieved rates of HPV vaccination approaching 70%, have become the target of cervical cancer screening programs. Here, we have analyzed the cervical cancer screening rates among the vaccinated and unvaccinated women. The survey data for cervical cancer screening at age 20 in FY 2015 was derived from two cities, Toyonaka and Iwaki. Among 2,727 females, in Toyonaka and Iwaki, who were born in FY 1995 and targeted in FY 2015 at age 20 for cervical cancer screening, their HPV vaccination rate was 64.2% (1,753/2,727). The screening rate was 6.4% (112/1,753) in the vaccinated and 3.9% (38/974) in the unvaccinated. This difference was statistically significant (p < 0.01). We have demonstrated that HPV-vaccinated females tended to be effectively protected from future cervical cancer than the unvaccinated.
Sections du résumé
BACKGROUND
The incidence of cervical cancer has been increasing, especially in younger generation, in Japan. The females born between 1994 and 1999, who achieved rates of HPV vaccination approaching 70%, have become the target of cervical cancer screening programs. Here, we have analyzed the cervical cancer screening rates among the vaccinated and unvaccinated women.
METHODS
The survey data for cervical cancer screening at age 20 in FY 2015 was derived from two cities, Toyonaka and Iwaki.
RESULTS
Among 2,727 females, in Toyonaka and Iwaki, who were born in FY 1995 and targeted in FY 2015 at age 20 for cervical cancer screening, their HPV vaccination rate was 64.2% (1,753/2,727). The screening rate was 6.4% (112/1,753) in the vaccinated and 3.9% (38/974) in the unvaccinated. This difference was statistically significant (p < 0.01).
CONCLUSIONS
We have demonstrated that HPV-vaccinated females tended to be effectively protected from future cervical cancer than the unvaccinated.
Identifiants
pubmed: 31272873
pii: S0264-410X(19)30839-4
doi: 10.1016/j.vaccine.2019.06.064
pii:
doi:
Substances chimiques
Papillomavirus Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4424-4426Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.