The Evolution of Erythrocytes Becoming Red in Respect to Fluorescence.
fluorescent protein
imaging
intravital microscopy
mouse model
transfusion
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2019
2019
Historique:
received:
15
03
2019
accepted:
31
05
2019
entrez:
6
7
2019
pubmed:
6
7
2019
medline:
6
7
2019
Statut:
epublish
Résumé
Very young red blood cells, namely reticulocytes, can be quite easily recognized and labeled by cluster of differentiation antibodies (CD71, transferrin receptor) or by staining remnant RNA with thiazol orange. In contrast, age specific erythrocyte labeling is more difficult in later periods of their life time. While erythrocytes contain band 4.1 protein, a molecular clock, so far it has not been possible to read this clock on individual cells. One concept to track erythrocytes during their life time is to mark them when they are young, either directly
Identifiants
pubmed: 31275166
doi: 10.3389/fphys.2019.00753
pmc: PMC6593091
doi:
Types de publication
Journal Article
Langues
eng
Pagination
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