Antithrombotics: From Aspirin to DOACs in Coronary Artery Disease and Atrial Fibrillation (Part 3/5).


Journal

Journal of the American College of Cardiology
ISSN: 1558-3597
Titre abrégé: J Am Coll Cardiol
Pays: United States
ID NLM: 8301365

Informations de publication

Date de publication:
06 08 2019
Historique:
received: 30 11 2018
revised: 22 01 2019
accepted: 04 02 2019
pubmed: 7 7 2019
medline: 19 5 2020
entrez: 7 7 2019
Statut: ppublish

Résumé

For secondary prevention of coronary artery disease (CAD), oral antiplatelet therapy is essential. In case of coronary intervention, temporary dual antiplatelet therapy is mandatory as well. Recently, low-dose oral anticoagulation has entered the CAD arena. Atrial fibrillation (AF) is often seen in CAD and vice versa. In most patients stroke prevention in AF consists of oral anticoagulation. In many cases of CAD in patients with AF, anticoagulation has to be combined with antiplatelet agents (so called, dual pathway antithrombotic therapy). Excess bleeding in these conditions is a rapidly rising problem. This review addresses the antithrombotic options in CAD alone, in AF alone, and in their combination, when either an invasive or a noninvasive approach has been chosen.

Identifiants

pubmed: 31277840
pii: S0735-1097(19)35400-2
doi: 10.1016/j.jacc.2019.02.080
pii:
doi:

Substances chimiques

Anticoagulants 0
Platelet Aggregation Inhibitors 0
Aspirin R16CO5Y76E

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

699-711

Informations de copyright

Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Auteurs

Freek W A Verheugt (FWA)

Department of Cardiology, Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, the Netherlands. Electronic address: f.w.a.verheugt@olvg.nl.

Jurriën M Ten Berg (JM)

Department of Cardiology, Sint-Antonius Ziekenhuis, Nieuwegein, the Netherlands.

Robert F Storey (RF)

Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom.

Thomas Cuisset (T)

Department of Cardiology, Timone University Hospital Center, Marseille, France.

Christopher B Granger (CB)

Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina.

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Classifications MeSH