Utility of open surgical lung biopsy in children.
Interstitial lung disease
Lung biopsy
Paediatrics
Journal
Pulmonary pharmacology & therapeutics
ISSN: 1522-9629
Titre abrégé: Pulm Pharmacol Ther
Pays: England
ID NLM: 9715279
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
02
08
2018
revised:
17
04
2019
accepted:
03
07
2019
pubmed:
8
7
2019
medline:
1
8
2020
entrez:
8
7
2019
Statut:
ppublish
Résumé
Open lung biopsy (OLB) is commonly used to obtain a definitive histological diagnosis in children with respiratory disorders. This allows correct treatment pathways to be followed and guides discussions surrounding prognosis. Our aim was to determine if OLB is useful in obtaining a conclusive diagnosis in a child with complex respiratory disease. In total, 179 OLB episodes were identified in children under 18 years from 2006 to 2016. Biopsies confirming congenital thoracic malformations or pulmonary metastatic disease were excluded. 42 patients had 44 episodes of OLB in the period studied. A definitive histological diagnosis was reached in 35 (79%) cases. There were no deaths directly attributable to OLB surgery. OLB contributed substantially in obtaining a definitive diagnosis for our patient population, no increase in mortality. It allowed targeted treatment and provided valuable prognostic information on the likely progression of the disease so families could plan for palliation where appropriate.
Identifiants
pubmed: 31279963
pii: S1094-5539(18)30191-3
doi: 10.1016/j.pupt.2019.101816
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101816Informations de copyright
Crown Copyright © 2019. Published by Elsevier Ltd. All rights reserved.