Diabetic ketoacidosis caused by fulminant type 1 diabetes during adjuvant chemotherapy for colon cancer: A case report.
adjuvant chemotherapy
colon cancer
diabetic ketoacidosis
fulminant type 1 diabetes
uracil-tegafur
Journal
Molecular and clinical oncology
ISSN: 2049-9450
Titre abrégé: Mol Clin Oncol
Pays: England
ID NLM: 101613422
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
27
08
2018
accepted:
05
04
2019
entrez:
9
7
2019
pubmed:
10
7
2019
medline:
10
7
2019
Statut:
ppublish
Résumé
Development of diabetic ketoacidosis (DKA) caused by fulminant type 1 diabetes (FT1D) during administration of uracil-tegafur (UFT) with leucovorin (LV) as adjuvant chemotherapy is extremely rare. Here, we report a case of DKA caused by FT1D during administration of UFT with LV as adjuvant chemotherapy for colon cancer. A woman in her 60s was transferred to the emergency medical center of our hospital with complaints of impaired consciousness and vomiting. She had undergone left hemicolectomy and D3 lymph node dissection for transverse colon cancer 8 months earlier. She was provided UFT with LV as adjuvant chemotherapy. Laboratory analysis revealed hyperglycemia, high anion gap metabolic acidosis and urinary ketones. She was diagnosed with DKA and was started on intravenous infusion of fluid and continuous subcutaneous insulin injections. Following admission, she was examined and diagnosed with FT1D. The present case describes an extremely rare case of DKA caused by FT1D during adjuvant chemotherapy with UFT + LV for colon cancer.
Identifiants
pubmed: 31281655
doi: 10.3892/mco.2019.1862
pii: MCO-0-0-1862
pmc: PMC6587009
doi:
Types de publication
Journal Article
Langues
eng
Pagination
189-191Références
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