Lateralizing Asymmetry of Adrenal Imaging and Adrenal Vein Sampling in Patients With Primary Aldosteronism.
adrenal vein 87 sampling
computed tomography
hypertension
left-right difference
primary aldosteronism
Journal
Journal of the Endocrine Society
ISSN: 2472-1972
Titre abrégé: J Endocr Soc
Pays: United States
ID NLM: 101697997
Informations de publication
Date de publication:
01 Jul 2019
01 Jul 2019
Historique:
received:
03
04
2019
accepted:
10
05
2019
entrez:
10
7
2019
pubmed:
10
7
2019
medline:
10
7
2019
Statut:
epublish
Résumé
In patients with primary aldosteronism (PA), it remains unclear whether aldosterone-producing adenomas are likely to develop in the left or right adrenal gland. To investigate left-right differences of PA laterality diagnoses via CT imaging and adrenal vein sampling (AVS). Retrospective, observational study. From the Japan Primary Aldosteronism Study, 1493 patients with PA were enrolled who underwent CT and ACTH-stimulated AVS. Left or right adrenal nodular lesion distribution and laterality observed on CT scans and from AVS were noted. Both on CT scans and AVS, unilateral results were observed more frequently on the left side than on the right side (25.1% vs 15.4% and 17.3% vs 13.5%, respectively; These results suggest aldosterone-producing adenomas and nonfunctioning tumors are more likely to develop on the left side in patients with PA and that misdiagnosis of CT-based lateralization may occur more frequently on the left side.
Identifiants
pubmed: 31286105
doi: 10.1210/js.2019-00131
pii: 201900131
pmc: PMC6608550
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1393-1402Références
Clin Endocrinol (Oxf). 2007 May;66(5):607-18
pubmed: 17492946
J Clin Endocrinol Metab. 2008 Apr;93(4):1366-71
pubmed: 18198224
Am J Kidney Dis. 2009 Jun;53(6):982-92
pubmed: 19339088
Ann Intern Med. 2009 Sep 1;151(5):329-37
pubmed: 19721021
Eur Radiol. 2010 Oct;20(10):2348-57
pubmed: 20521055
Radiology. 2010 Aug;256(2):504-10
pubmed: 20656838
Endocr J. 2011;58(9):711-21
pubmed: 21828936
Chin Med Sci J. 2013 Jan;27(4):220-4
pubmed: 23294587
Endocrinol Metab (Seoul). 2013 Mar;28(1):20-5
pubmed: 24396646
Hypertens Res. 2014 Apr;37(4):253-390
pubmed: 24705419
J Clin Endocrinol Metab. 2014 Dec;99(12):4462-70
pubmed: 25238207
Acad Radiol. 2014 Nov;21(11):1465-74
pubmed: 25300724
Eur Radiol. 2016 Aug;26(8):2494-501
pubmed: 26515550
J Clin Endocrinol Metab. 2016 Jul;101(7):2826-35
pubmed: 27172433
Lancet Diabetes Endocrinol. 2016 Sep;4(9):739-746
pubmed: 27325147
Eur J Clin Invest. 2017 May;47(5):372-377
pubmed: 28299775
Lancet Diabetes Endocrinol. 2017 Sep;5(9):689-699
pubmed: 28576687
J Endocr Soc. 2018 Mar 16;2(4):374-385
pubmed: 29644340
J Endocr Soc. 2018 Mar 22;2(5):398-407
pubmed: 29687091
J Clin Endocrinol Metab. 2019 Jun 1;104(6):1900-1906
pubmed: 30590677