The association between induction of labour at 38 to 39 weeks pregnancy and indication for caesarean delivery: An observational study.


Journal

The Australian & New Zealand journal of obstetrics & gynaecology
ISSN: 1479-828X
Titre abrégé: Aust N Z J Obstet Gynaecol
Pays: Australia
ID NLM: 0001027

Informations de publication

Date de publication:
12 2019
Historique:
received: 18 09 2018
accepted: 02 05 2019
pubmed: 10 7 2019
medline: 5 9 2020
entrez: 10 7 2019
Statut: ppublish

Résumé

Induction of labour is associated with a reduction in caesarean delivery, but the mechanism of action and which groups of women might benefit remain unknown. To assess the association between induction of labour at 38-39 weeks pregnancy, and caesarean delivery: (i) overall; (ii) for slow progress in labour; and (iii) for suspected fetal compromise. Retrospective observational study in two Sydney hospitals from 2009 to 2016, among nulliparous women with induction of labour at 38 or 39 completed weeks pregnancy and a singleton, cephalic presenting fetus. The comparator was all planned vaginal births beyond 39 There were 2388 and 15 259 women in the study and comparison groups respectively. Induction of labour was associated with caesarean delivery overall only for women <25 years of age (adjusted odds ratio 1.63; 95% CI 1.17-2.27) and was not associated with caesarean delivery for slow progress. Induction of labour was positively associated with increased caesarean delivery for suspected fetal compromise among young women (<30 years), with the association weakening as maternal age increased. The association between induction of labour and caesarean delivery was different for slow progress compared with suspected compromise (P = 0.005). Induction of labour has different effects on the likelihood of caesarean delivery for slow progress and for suspected fetal compromise. Women <30 years of age are at higher risk of caesarean delivery for suspected fetal compromise, potentially due to uterine hyperstimulation.

Sections du résumé

BACKGROUND
Induction of labour is associated with a reduction in caesarean delivery, but the mechanism of action and which groups of women might benefit remain unknown.
AIMS
To assess the association between induction of labour at 38-39 weeks pregnancy, and caesarean delivery: (i) overall; (ii) for slow progress in labour; and (iii) for suspected fetal compromise.
MATERIAL AND METHODS
Retrospective observational study in two Sydney hospitals from 2009 to 2016, among nulliparous women with induction of labour at 38 or 39 completed weeks pregnancy and a singleton, cephalic presenting fetus. The comparator was all planned vaginal births beyond 39
RESULTS
There were 2388 and 15 259 women in the study and comparison groups respectively. Induction of labour was associated with caesarean delivery overall only for women <25 years of age (adjusted odds ratio 1.63; 95% CI 1.17-2.27) and was not associated with caesarean delivery for slow progress. Induction of labour was positively associated with increased caesarean delivery for suspected fetal compromise among young women (<30 years), with the association weakening as maternal age increased. The association between induction of labour and caesarean delivery was different for slow progress compared with suspected compromise (P = 0.005).
CONCLUSIONS
Induction of labour has different effects on the likelihood of caesarean delivery for slow progress and for suspected fetal compromise. Women <30 years of age are at higher risk of caesarean delivery for suspected fetal compromise, potentially due to uterine hyperstimulation.

Identifiants

pubmed: 31287155
doi: 10.1111/ajo.13006
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

791-798

Subventions

Organisme : Albert McKern Scholarship through the University of Sydney
Pays : International
Organisme : NHMRC
ID : APP1144911
Pays : International

Informations de copyright

© 2019 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

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Auteurs

Bradley Stephen de Vries (BS)

School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
RPA Women and Babies, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Kevin McGeechan (K)

School of Public Health, University of Sydney, Sydney, New South Wales, Australia.

Alexandra Barratt (A)

Wiser Health Care, School of Public Health, University of Sydney, Sydney, New South Wales, Australia.

Jane Tooher (J)

RPA Women and Babies, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Ebony Wong (E)

RPA Women and Babies, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Hala Phipps (H)

Sydney Local Area Health District, Sydney, New South Wales, Australia.

Adrienne Gordon (A)

Discipline of Obstetrics, Gynaecology and Neonatology, University of Sydney, Sydney, New South Wales, Australia.
Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.

Jon Anthony Hyett (JA)

Department of High Risk Obstetrics, RPA Women and Babies, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Central Clinical School, Discipline of Obstetrics, Gynaecology and Neonatology, University of Sydney, Sydney, New South Wales, Australia.

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