Evaluation of oxidative stress mechanisms and the effects of phytotherapic extracts on Parkinson's disease
Animals
Antioxidants
/ pharmacology
Disease Models, Animal
Drosophila melanogaster
/ metabolism
Mice, Transgenic
Mitochondria
/ drug effects
Oxidative Stress
/ drug effects
Parkinson Disease
/ drug therapy
Plant Extracts
/ pharmacology
Protein Kinases
/ drug effects
Protein Serine-Threonine Kinases
/ drug effects
Drosophila melanogaster
PINK1B9 mutants
phytotherapic preparations
telomere length
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
01 10 2019
01 10 2019
Historique:
pubmed:
12
7
2019
medline:
2
6
2020
entrez:
12
7
2019
Statut:
ppublish
Résumé
Oxidative stress is commonly observed in both idiopathic and genetic cases of Parkinson's disease (PD). It plays an important role in the degeneration of dopaminergic neurons, and it has been associated with altered telomere length (TL). There is currently no cure for PD, and extracts of antioxidative plant, such as
Identifiants
pubmed: 31291788
doi: 10.1096/fj.201901010
doi:
Substances chimiques
Antioxidants
0
Plant Extracts
0
Protein Kinases
EC 2.7.-
Protein Serine-Threonine Kinases
EC 2.7.11.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM