Single-Dose Vaccination with a Hepatotropic Adeno-associated Virus Efficiently Localizes T Cell Immunity in the Liver with the Potential To Confer Rapid Protection against Hepatitis C Virus.


Journal

Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724

Informations de publication

Date de publication:
01 10 2019
Historique:
received: 22 02 2019
accepted: 03 07 2019
pubmed: 12 7 2019
medline: 3 6 2020
entrez: 12 7 2019
Statut: epublish

Résumé

Hepatitis C virus (HCV) is a significant contributor to the global disease burden, and development of an effective vaccine is required to eliminate HCV infections worldwide. CD4

Identifiants

pubmed: 31292249
pii: JVI.00202-19
doi: 10.1128/JVI.00202-19
pmc: PMC6744243
pii:
doi:

Substances chimiques

Drug Carriers 0
Isoantigens 0
Vaccines, DNA 0
Viral Nonstructural Proteins 0
Viral Vaccines 0
liver specific F antigen 0
NS-5 protein, hepatitis C virus EC 2.7.7.48

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2019 American Society for Microbiology.

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Auteurs

Zelalem A Mekonnen (ZA)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Branka Grubor-Bauk (B)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Kieran English (K)

Liver Immunology Group and A. W. Morrow Gastroenterology and Liver Centre, Centenary Institute, Royal Prince Alfred Hospital and University of Sydney, Newtown, NSW, Australia.

Preston Leung (P)

Viral Immunology Systems Program, The Kirby Institute, The University of New South Wales, Sydney, NSW, Australia.

Makutiro G Masavuli (MG)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Ashish C Shrestha (AC)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Patrick Bertolino (P)

Liver Immunology Group and A. W. Morrow Gastroenterology and Liver Centre, Centenary Institute, Royal Prince Alfred Hospital and University of Sydney, Newtown, NSW, Australia.

David G Bowen (DG)

Liver Immunology Group and A. W. Morrow Gastroenterology and Liver Centre, Centenary Institute, Royal Prince Alfred Hospital and University of Sydney, Newtown, NSW, Australia.
Collaborative Transplantation Research Group, Bosch Institute, Royal Prince Alfred Hospital and University of Sydney, Newtown, NSW, Australia.

Andrew R Lloyd (AR)

Viral Immunology Systems Program, The Kirby Institute, The University of New South Wales, Sydney, NSW, Australia.

Eric J Gowans (EJ)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Danushka K Wijesundara (DK)

Virology Laboratory, Basil Hetzel Institute for Translational Health Research, Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia danushka.wijesundara@adelaide.edu.au.

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Classifications MeSH