Optical Coherence Tomography Angiography Evaluation of Conjunctival Vessels During Filtering Surgery.

conjunctival vessels filtering blebs filtering surgery ocular coherence tomography angiography

Journal

Translational vision science & technology
ISSN: 2164-2591
Titre abrégé: Transl Vis Sci Technol
Pays: United States
ID NLM: 101595919

Informations de publication

Date de publication:
2019
Historique:
received: 11 06 2018
accepted: 19 03 2019
entrez: 12 7 2019
pubmed: 12 7 2019
medline: 12 7 2019
Statut: epublish

Résumé

To evaluate the changes in conjunctival vascularization with optical coherence tomography angiography (OCT-A) before and after filtering surgery and to correlate these results with filtering surgery success. We evaluated 20 blebs of 20 patients after a first-time trabeculectomy. Conjunctival vascularization was quantified using ImageJ software. Eyes were classified into two groups according to the preoperative conjunctival vessel density: hypovascularized conjunctiva (HypoV; 10 eyes) and hypervascularized conjunctiva (HyperV; 10 eyes). The density of intraepithelial microcysts (0 to 3) was also analyzed. There were significantly more needling procedures in the HyperV group, with 70% of the eyes undergoing needling during follow-up compared to 20% in the HypoV group ( Poor conjunctival vascularization was associated with lower IOP and a higher number of intraepithelial microcysts evaluated with OCT-A. OCT-A provides a simple, noninvasive, and reproducible method to analyze and quantify bleb vessels before and after filtering surgery. Several studies have demonstrated that highly vascularized blebs might be associated with a higher risk of failure. OCT-A may provide a dye-free, noncontact method for monitoring conjunctival vascularization after filtering surgery.

Identifiants

pubmed: 31293822
doi: 10.1167/tvst.8.4.4
pii: TVST-18-0931
pmc: PMC6613592
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4

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Auteurs

Stéphanie Hayek (S)

Department of Ophthalmology III, Quinze-Vingts Hospital, Paris, France.
Quinze-Vingts Hospital, DHU Sight Restore, INSERM-DHOS CIC, Paris, France.

Antoine Labbé (A)

Department of Ophthalmology III, Quinze-Vingts Hospital, Paris, France.
Quinze-Vingts Hospital, DHU Sight Restore, INSERM-DHOS CIC, Paris, France.
INSERM, U968, Paris, France.
Sorbonne Universités, UPMC Université Paris 06, Paris, France.
CNRS, UMR 7210, Paris, France.
Department of Ophthalmology, Ambroise Paré Hospital, APHP, University of Paris, Saclay, France.

Emmanuelle Brasnu (E)

Department of Ophthalmology III, Quinze-Vingts Hospital, Paris, France.
Quinze-Vingts Hospital, DHU Sight Restore, INSERM-DHOS CIC, Paris, France.

Pascale Hamard (P)

Department of Ophthalmology III, Quinze-Vingts Hospital, Paris, France.
Quinze-Vingts Hospital, DHU Sight Restore, INSERM-DHOS CIC, Paris, France.

Christophe Baudouin (C)

Department of Ophthalmology III, Quinze-Vingts Hospital, Paris, France.
Quinze-Vingts Hospital, DHU Sight Restore, INSERM-DHOS CIC, Paris, France.
INSERM, U968, Paris, France.
Sorbonne Universités, UPMC Université Paris 06, Paris, France.
CNRS, UMR 7210, Paris, France.
Department of Ophthalmology, Ambroise Paré Hospital, APHP, University of Paris, Saclay, France.

Classifications MeSH