[Visceral leishmaniasis].
Viszerale Leishmaniose.
Epidemiology
Hepatosplenomegaly
Immunosuppression
Opportunistic infection
Surgical aspects
Journal
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
ISSN: 1433-0385
Titre abrégé: Chirurg
Pays: Germany
ID NLM: 16140410R
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
pubmed:
13
7
2019
medline:
31
10
2019
entrez:
13
7
2019
Statut:
ppublish
Résumé
Visceral leishmaniasis is a worldwide distributed infectious zoonotic disease caused by protozoan pathogens of the genus Leishmania which are transmitted by sandflies. The main hosts are dogs. The prevalence in Germany is low. Predominantly affected are migrants and travelers returning from Mediterranean countries. The main clinical symptoms are fever, hepatosplenomegaly and pancytopenia. The diagnosis is made by polymerase chain reaction of peripheral blood or direct detection of Leishmania in bone marrow aspirates. Lesions of the liver and spleen can easily be misinterpreted as numerous benign or malignant differential diagnoses. Treatment is always systemic with antiparasitic drugs. Immunosuppressed patients with HIV co-infection or after solid organ transplantation are prone to infection as well as atypical and severe courses.
Identifiants
pubmed: 31297548
doi: 10.1007/s00104-019-0994-1
pii: 10.1007/s00104-019-0994-1
doi:
Substances chimiques
Antiprotozoal Agents
0
Types de publication
Journal Article
Review
Langues
ger
Sous-ensembles de citation
IM
Pagination
833-837Références
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