[Clinical presentation and performance of urine dipstick for diagnosis of urinary infection in geriatric population].

Présentation clinique et performance de la bandelette urinaire pour le diagnostic d’infection urinaire en population gériatrique.

Journal

La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 26 01 2019
revised: 12 06 2019
accepted: 17 06 2019
pubmed: 16 7 2019
medline: 7 5 2020
entrez: 15 7 2019
Statut: ppublish

Résumé

Urinary tract infections (UTI) are the second cause of community-acquired bacterial infections in the elderly. Distinguishing symptomatic UTI from asymptomatic bacteriuria is problematic, as older adults are less likely to present with localized urinary symptoms. We evaluated characteristics of patients presenting UTI among elderly with sepsis. Moreover, we aimed to evaluate the sensibility and specificity of urine dipstick tests in the diagnosis of UTI in geriatric population. We led a prospective, monocentric, observational study between April 2017 and January 2018. We included patients hospitalized in geriatric wards, who were prescribed urine culture for UTI symptoms or/and infection without primary sites for which a urine culture was prescribed. Dipstick urinalyses were performed for all patients. Clinical and biological characteristics of all patients were compared according to the final diagnosis of UTI. Moreover, results of dipstick tests were evaluated for the diagnosis of UTI in this population. Among 165 patients, 67 (40.6 %) had a UTI and 98 (59.4 %) had another diagnosis. These two groups were comparable for age and daily-living activities. In the UTI group, the proportion of women was higher than in the other group (P<0.05), and mean MMSE score was lower (P<0.05). Positive urine dipstick test for leukocytes and/or nitrites had high sensitivity (92 %), but low specificity (50 %). Negative predictive value of this test was high (91 %). For suspicion of UTI among elderly, few criteria are specific. Negative dipstick tests can suggest an absence of UTI due to its high negative predictive value.

Sections du résumé

BACKGROUND BACKGROUND
Urinary tract infections (UTI) are the second cause of community-acquired bacterial infections in the elderly. Distinguishing symptomatic UTI from asymptomatic bacteriuria is problematic, as older adults are less likely to present with localized urinary symptoms. We evaluated characteristics of patients presenting UTI among elderly with sepsis. Moreover, we aimed to evaluate the sensibility and specificity of urine dipstick tests in the diagnosis of UTI in geriatric population.
PATIENTS AND METHOD METHODS
We led a prospective, monocentric, observational study between April 2017 and January 2018. We included patients hospitalized in geriatric wards, who were prescribed urine culture for UTI symptoms or/and infection without primary sites for which a urine culture was prescribed. Dipstick urinalyses were performed for all patients. Clinical and biological characteristics of all patients were compared according to the final diagnosis of UTI. Moreover, results of dipstick tests were evaluated for the diagnosis of UTI in this population.
RESULTS RESULTS
Among 165 patients, 67 (40.6 %) had a UTI and 98 (59.4 %) had another diagnosis. These two groups were comparable for age and daily-living activities. In the UTI group, the proportion of women was higher than in the other group (P<0.05), and mean MMSE score was lower (P<0.05). Positive urine dipstick test for leukocytes and/or nitrites had high sensitivity (92 %), but low specificity (50 %). Negative predictive value of this test was high (91 %).
CONCLUSION CONCLUSIONS
For suspicion of UTI among elderly, few criteria are specific. Negative dipstick tests can suggest an absence of UTI due to its high negative predictive value.

Identifiants

pubmed: 31301943
pii: S0248-8663(19)30556-9
doi: 10.1016/j.revmed.2019.06.010
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

fre

Sous-ensembles de citation

IM

Pagination

714-721

Informations de copyright

Copyright © 2019 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

M Coudert (M)

Unité de court séjour gériatrique, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

M Pépin (M)

Unité de court séjour gériatrique, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

A de Thezy (A)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

E Fercot (E)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

M Laycuras (M)

Centre médical des armées (CMA) de Angers, Le Mans - Saumur, 106, rue Eblé, 49041 Angers, France.

A-L Coudert (AL)

Faculté de médecine de Limoges, 2, rue du Docteur Marcland, 87025 Limoges, France.

C Duran (C)

Unité des maladies infectieuses, hôpital Raymond-Poincaré, AP-HP, 104, boulevard Raymond-Poincaré, 92380 Garches, France.

F Bouchand (F)

Pharmacie, hôpital Raymond-Poincaré, AP-HP, 104, boulevard Raymond-Poincaré, 92380 Garches, France.

B Davido (B)

Unité des maladies infectieuses, hôpital Raymond-Poincaré, AP-HP, 104, boulevard Raymond-Poincaré, 92380 Garches, France.

M Le Crane (M)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

B Denis (B)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

F Muller (F)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

M Gourdon (M)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

C-L Peng (CL)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

R Mahamdia (R)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

Z Mekerta (Z)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

Z Seridi (Z)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

J-L Gaillard (JL)

Service de microbiologie, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

L Leichowski (L)

Soins de suite et rééducation gériatrique, hôpital Sainte-Périne, AP-HP, 11, rue Chardon-Lagache, 75016 Paris, France.

S Moulias (S)

Unité de court séjour gériatrique, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

M Rottman (M)

Service de microbiologie, hôpital Raymond-Poincaré, AP-HP, 104, boulevard Raymond-Poincaré, 92380 Garches, France.

V Sivadon-Tardy (V)

Service de microbiologie, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

L Teillet (L)

Unité de court séjour gériatrique, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.

A Dinh (A)

Centre médical des armées (CMA) de Angers, Le Mans - Saumur, 106, rue Eblé, 49041 Angers, France. Electronic address: aurelien.dinh@aphp.fr.

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Classifications MeSH