Total-Body Dynamic Reconstruction and Parametric Imaging on the uEXPLORER.
PET
direct reconstruction
kernel method
total-body parametric imaging
tracer kinetics
Journal
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
01
05
2019
accepted:
06
07
2019
pubmed:
16
7
2019
medline:
25
7
2020
entrez:
15
7
2019
Statut:
ppublish
Résumé
The world's first 194-cm-long total-body PET/CT scanner (uEXPLORER) has been built by the EXPLORER Consortium to offer a transformative platform for human molecular imaging in clinical research and health care. Its total-body coverage and ultra-high sensitivity provide opportunities for more accurate tracer kinetic analysis in studies of physiology, biochemistry, and pharmacology. The objective of this study was to demonstrate the capability of total-body parametric imaging and to quantify the improvement in image quality and kinetic parameter estimation by direct and kernel reconstruction of the uEXPLORER data.
Identifiants
pubmed: 31302637
pii: jnumed.119.230565
doi: 10.2967/jnumed.119.230565
pmc: PMC8801950
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
285-291Subventions
Organisme : NCI NIH HHS
ID : R01 CA206187
Pays : United States
Informations de copyright
© 2020 by the Society of Nuclear Medicine and Molecular Imaging.
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