Assessment of The Bethesda System for Reporting Thyroid Cytopathology.
Atypia of undetermined significance/follicular lesion of undetermined significance
Bethesda
Cytopathology
FNA
Fine-needle aspiration
Follicular neoplasm/suspicious for follicular neoplasm
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)
Papillary thyroid carcinoma
Risk of malignancy
Thyroid
Journal
American journal of clinical pathology
ISSN: 1943-7722
Titre abrégé: Am J Clin Pathol
Pays: England
ID NLM: 0370470
Informations de publication
Date de publication:
09 09 2019
09 09 2019
Historique:
pubmed:
16
7
2019
medline:
26
3
2020
entrez:
16
7
2019
Statut:
ppublish
Résumé
Long-term follow-up is important for determining performance characteristics of thyroid fine-needle aspiration (FNA). Histologic or 3 or more years of clinical follow-up was used to calculate performance characteristics of thyroid FNA before and after implementation of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The impact of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) classification was also investigated. Follow-up was obtained for 1,277/1,134 and 1,616/1,393 aspirates/patients (median clinical follow-up, 9.9 and 4.4 years, pre- and post-TBSRTC, respectively). Nondiagnostic, suspicious for follicular neoplasm, and suspicious for malignancy (SFM) diagnoses decreased and benign diagnoses increased post-TBSRTC, while atypical rate remained less than 1%. Negative predictive value for benign nodules and positive predictive value (PPV) for SFM increased significantly. Eleven nodules were reclassified as NIFTP, slightly decreasing PPV/risk of malignancy (ROM). Appropriate ROM for thyroid FNA can be achieved through application of TBSRTC terminology with minimal use of atypical category.
Identifiants
pubmed: 31305880
pii: 5532286
doi: 10.1093/ajcp/aqz076
pmc: PMC8204148
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
502-511Subventions
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Informations de copyright
© American Society for Clinical Pathology, 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Références
Am J Clin Pathol. 2015 Dec;144(6):850-7
pubmed: 26572991
Am J Clin Pathol. 2011 May;135(5):770-5
pubmed: 21502433
Clin Endocrinol (Oxf). 2017 Dec;87(6):825-831
pubmed: 28718944
Thyroid. 2011 Mar;21(3):243-51
pubmed: 21190442
Cancer Cytopathol. 2012 Apr 25;120(2):108-10
pubmed: 21928363
Pathology. 2014 Dec;46(7):592-5
pubmed: 25393248
Cancer. 2009 Jun 25;117(3):195-202
pubmed: 19382174
Cancer. 2007 Oct 25;111(5):306-15
pubmed: 17680588
Diagn Cytopathol. 2010 Oct;38(10):731-9
pubmed: 20049964
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
J Clin Endocrinol Metab. 2014 Jan;99(1):119-25
pubmed: 24152684
BMC Med. 2016 Jan 27;14:11
pubmed: 26817603
Cancer Cytopathol. 2015 Dec;123(12):713-22
pubmed: 26355876
Am J Clin Pathol. 2010 Sep;134(3):450-6
pubmed: 20716802
Surgery. 2008 Dec;144(6):1038-43; discussion 1043
pubmed: 19041015
J Cytol. 2017 Jul-Sep;34(3):144-148
pubmed: 28701827
Surgery. 2015 Mar;157(3):510-7
pubmed: 25633738
Surgery. 2010 Dec;148(6):1267-72; discussion 1272-3
pubmed: 21134560
JAMA Oncol. 2016 Aug 1;2(8):1023-9
pubmed: 27078145
Diagn Cytopathol. 2009 Oct;37(10):710-4
pubmed: 19373907
J Clin Endocrinol Metab. 2013 Nov;98(11):E1852-60
pubmed: 23979959
Thyroid. 2015 Jul;25(7):760-8
pubmed: 26058403
Cancer Cytopathol. 2010 Aug 25;118(4):186-9
pubmed: 20586118
Hum Pathol. 2016 Aug;54:134-42
pubmed: 27085556
Am J Clin Pathol. 2017 Dec 20;149(1):50-54
pubmed: 29272354
Cancer Cytopathol. 2016 Mar;124(3):181-7
pubmed: 26457584
Can Assoc Radiol J. 2013 Aug;64(3):220-5
pubmed: 22867963
Endocrine. 2016 Sep;53(3):651-61
pubmed: 27071659
Am J Surg Pathol. 2002 Nov;26(11):1508-14
pubmed: 12409728
Ann Intern Med. 2013 Sep 3;159(5):325-32
pubmed: 24026318
Ann Surg Oncol. 2014 Oct;21(11):3522-7
pubmed: 24796967
Acta Cytol. 2012;56(4):333-9
pubmed: 22846422
Thyroid. 2015 Sep;25(9):987-92
pubmed: 26114752
Thyroid. 2016 Jan;26(1):1-133
pubmed: 26462967
Thyroid. 2009 Nov;19(11):1215-23
pubmed: 19888859
Cancer Cytopathol. 2010 Feb 25;118(1):17-23
pubmed: 20099311
Acta Cytol. 2016;60(3):198-204
pubmed: 27414983
Am J Surg Pathol. 2004 Oct;28(10):1336-40
pubmed: 15371949
Cancer Cytopathol. 2011 Feb 25;119(1):68-73
pubmed: 21140483
Surgery. 2013 Dec;154(6):1420-6; discussion 1426-7
pubmed: 24094448