Brain 123I-FP-CIT SPECT of a Holmes Tremor Due to Midbrain Pilocytic Astrocytoma.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
pubmed:
16
7
2019
medline:
23
2
2020
entrez:
16
7
2019
Statut:
ppublish
Résumé
A 24-year-old woman with an unresectable right mesencephalic pilocytic astrocytoma was treated with stereotaxic radiation therapy. Three months after a radiation therapy-induced bleeding, she presented a severe disabling low frequency rest and kinetic tremor involving the left upper limb, associated with dystonia, and a Holmes tremor was suspected. Thereby, we performed a I-FP-CIT SPECT (DATSCAN) that revealed a normal distribution of radiotracer over the left striatum, whereas no binding was seen in the right caudate and putamen. This pattern was consistent with a right severe nigrostriatal dopaminergic denervation due to an ipsilateral red nucleus injury.
Identifiants
pubmed: 31306206
doi: 10.1097/RLU.0000000000002729
pii: 00003072-202001000-00037
doi:
Substances chimiques
Tropanes
0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
155797-99-2
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e46-e47Références
Guedj E, Witjas T, Azulay JP, et al. Neuroimaging findings in a case of Holmes tremor. Clin Nucl Med. 2007;32:139–140.
Juri C, Chana P, Kramer V, et al. Imaging nigrostriatal dopaminergic deficit in Holmes tremor with 18F-PR04.MZ-PET/CT. Clin Nucl Med. 2015;40:740–741.
Schreuder FH, Hamers RM, van Domburg PH. Teaching NeuroImages: Holmes tremor after midbrain stroke. Neurology. 2010;75:e10.
Sung YF, Hsu YD, Huang WS. (99m)Tc-TRODAT-1 SPECT study in evaluation of Holmes tremor after thalamic hemorrhage. Ann Nucl Med. 2009;23:605–608.
Kim MC, Son BC, Miyagi Y, et al. Vim thalamotomy for Holmes' tremor secondary to midbrain tumour. J Neurol Neurosurg Psychiatry. 2002;73:453–455.
Gajos A, Budrewicz S, Koszewicz M, et al. Is nigrostriatal dopaminergic deficit necessary for Holmes tremor to develop? The DaTSCAN and IBZM SPECT study. J Neural Transm (Vienna). 2017;124:1389–1393.
Seidel S, Kasprian G, Leutmezer F, et al. Disruption of nigrostriatal and cerebellothalamic pathways in dopamine responsive Holmes' tremor. J Neurol Neurosurg Psychiatry. 2009;80:921–923.
Bukowczan S, Rudzińska M, Banach M, et al. Holmes' tremor is rare kind of tremor caused by lesion of rubro-spinal tract. Neurol Neurochir Pol. 2003;37(Suppl 5):83–88.