Myo-inositol in the protection from cadmium-induced toxicity in mice kidney: An emerging nutraceutical challenge.
Animals
Antioxidants
/ administration & dosage
Blood Urea Nitrogen
Cadmium Chloride
/ toxicity
Creatinine
/ blood
Dietary Supplements
Glutathione
/ metabolism
Glutathione Peroxidase
/ metabolism
Inositol
/ pharmacology
Kidney
/ drug effects
Male
Mice
Mice, Inbred C57BL
Nitric Oxide Synthase Type II
/ metabolism
Tumor Necrosis Factor-alpha
/ metabolism
Cadmium
KIM-1
Kidney
MIOX
Myo-inositol
Nutraceutical
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
30
04
2019
revised:
21
06
2019
accepted:
11
07
2019
pubmed:
16
7
2019
medline:
18
12
2019
entrez:
16
7
2019
Statut:
ppublish
Résumé
Cadmium (Cd) induces functional and morphological changes in kidney. Therefore, the effects of a natural nutraceutical antioxidant, myo-inositol (MI), were evaluated in mice kidneys after Cd challenge. Twenty-eight C57 BL/6 J mice were divided into these groups: 0.9% NaCl; MI (360 mg/kg/day); CdCl
Identifiants
pubmed: 31306689
pii: S0278-6915(19)30464-8
doi: 10.1016/j.fct.2019.110675
pii:
doi:
Substances chimiques
Antioxidants
0
Tumor Necrosis Factor-alpha
0
Inositol
4L6452S749
Creatinine
AYI8EX34EU
Glutathione Peroxidase
EC 1.11.1.9
Nitric Oxide Synthase Type II
EC 1.14.13.39
Glutathione
GAN16C9B8O
Cadmium Chloride
J6K4F9V3BA
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110675Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.