Heterobimetallic nickel(II) and palladium(II) complexes derived from S-benzyl-N- (ferrocenyl)methylenedithiocarbazate: Trypanocidal activity and interaction with Trypanosoma cruzi Old Yellow Enzyme (TcOYE).
Animals
Benzyl Compounds
/ pharmacology
Cell Survival
/ drug effects
Coordination Complexes
/ chemistry
Dose-Response Relationship, Drug
Enzyme Inhibitors
/ chemistry
Humans
Hydrazines
/ chemistry
Macaca mulatta
Metallocenes
/ chemistry
Molecular Docking Simulation
Molecular Structure
NADPH Dehydrogenase
/ antagonists & inhibitors
Nickel
/ chemistry
Palladium
/ chemistry
Structure-Activity Relationship
Trypanocidal Agents
/ chemistry
Trypanosoma cruzi
/ drug effects
Chagas disease
Dithiocarbazates
Heterobimetallic complexes
Nickel(II) complexes
Palladium(II) complexes
TcOYE
Journal
European journal of medicinal chemistry
ISSN: 1768-3254
Titre abrégé: Eur J Med Chem
Pays: France
ID NLM: 0420510
Informations de publication
Date de publication:
15 Oct 2019
15 Oct 2019
Historique:
received:
21
01
2019
revised:
10
06
2019
accepted:
04
07
2019
pubmed:
16
7
2019
medline:
5
11
2019
entrez:
16
7
2019
Statut:
ppublish
Résumé
Reactions of Ni(II) and Pd(II) precursors with S-benzyl-N-(ferrocenyl)methylenedithiocarbazate (HFedtc) led to the formation of heterobimetallic complexes of the type [M
Identifiants
pubmed: 31306908
pii: S0223-5234(19)30635-X
doi: 10.1016/j.ejmech.2019.07.014
pii:
doi:
Substances chimiques
Benzyl Compounds
0
Coordination Complexes
0
Enzyme Inhibitors
0
Hydrazines
0
Metallocenes
0
Trypanocidal Agents
0
Palladium
5TWQ1V240M
Nickel
7OV03QG267
NADPH Dehydrogenase
EC 1.6.99.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
213-223Informations de copyright
Copyright © 2019 Elsevier Masson SAS. All rights reserved.