A dansyl fluorescent pH probe with wide responsive range in aqueous solution.
Dansyl group
Fluorescence probe
Wide pH range
pH sensitivity
Journal
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533
Informations de publication
Date de publication:
05 Dec 2019
05 Dec 2019
Historique:
received:
12
04
2019
revised:
01
07
2019
accepted:
07
07
2019
pubmed:
16
7
2019
medline:
16
7
2019
entrez:
16
7
2019
Statut:
ppublish
Résumé
A fluorescent pH probe based on diphenylalanine-modified dansyl (FF-Dns) was designed and synthesized. The probe showed sensitive fluorescence emission to pH change over a wide range of 1-13 in aqueous solution. At pH 4-10, FF-Dns displayed the characteristic fluorescent emission of dansyl group (yellow); while protonation of the dimethylamino group caused a very weak fluorescence emission at pH 1-4, and deprotonation of the sulfonamide group caused an emission blue-shift to the green region at pH 11-13. These properties endow FF-Dns with the potential to detect pH variation in physiological environments.
Identifiants
pubmed: 31306960
pii: S1386-1425(19)30738-3
doi: 10.1016/j.saa.2019.117348
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
117348Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.