Coagulation and anticoagulation in the intraoperative setting.
Anticoagulants
Coagulation
Embolism
Fibrinolysis
Perioperative bleeding
Thrombosis
Journal
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
ISSN: 1473-0502
Titre abrégé: Transfus Apher Sci
Pays: England
ID NLM: 101095653
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
pubmed:
17
7
2019
medline:
23
1
2020
entrez:
17
7
2019
Statut:
ppublish
Résumé
Adequate function of the coagulation system is vital for an uncomplicated outcome of surgery. Clinically relevant perioperative bleeding complications may occur when surgical hemostasis is inadequate, but can also be caused by insufficient activity of the hemostatic system. Optimal surgical hemostasis and a satisfactory function of the coagulation system are complementary. In this article current insights on normal function and dysfunction of the coagulation system are reviewed as well as drugs that may affect a proper hemostatic response. We discuss coagulation disorders resulting in increased perioperative blood loss and conditions that may enhance the threat of postoperative thrombosis.
Identifiants
pubmed: 31307835
pii: S1473-0502(19)30106-5
doi: 10.1016/j.transci.2019.06.013
pii:
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Journal Article
Review
Langues
eng
Pagination
386-391Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.