Intravenous immunoglobulin therapy: a snapshot for the internist.


Journal

Internal and emergency medicine
ISSN: 1970-9366
Titre abrégé: Intern Emerg Med
Pays: Italy
ID NLM: 101263418

Informations de publication

Date de publication:
10 2019
Historique:
received: 24 05 2019
accepted: 05 07 2019
pubmed: 17 7 2019
medline: 9 4 2020
entrez: 17 7 2019
Statut: ppublish

Résumé

Intravenous immunoglobulins are the cornerstone for the treatment of primary humoral immunodeficiencies and may be used for a great number of other autoimmune, neurological and hematological conditions as well. Given their wide application, the possibility of running across a patient who needs this kind of therapy is becoming increasingly common. Generally, intravenous immunoglobulins are well tolerated. However, numerous adverse reactions ranging from mild to severe have been reported and linked to patient- and product-related factors. For all these reasons, we present herein a comprehensive review of the on- and off-label applications of intravenous immunoglobulins and provide a guide for the internist how to minimize the risk of adverse reactions and manage them.

Identifiants

pubmed: 31309519
doi: 10.1007/s11739-019-02150-z
pii: 10.1007/s11739-019-02150-z
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1041-1049

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Auteurs

Gianfranco Vitiello (G)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy. gianfranco.vitiello@unifi.it.

Giacomo Emmi (G)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.

Elena Silvestri (E)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.

Gerardo Di Scala (G)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.

Boaz Palterer (B)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.

Paola Parronchi (P)

Experimental and Clinical Medicine Department, University of Firenze, Largo Brambilla 3, 50100, Firenze, Italy.

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Classifications MeSH