Investigation of the Effects of Biochemical Parameters on Alzheimer's Disease.
Alzheimer’s disease
MMSE
biochemical values
biochemistry
dementia
geriatrics
parameters
Journal
American journal of Alzheimer's disease and other dementias
ISSN: 1938-2731
Titre abrégé: Am J Alzheimers Dis Other Demen
Pays: United States
ID NLM: 101082834
Informations de publication
Date de publication:
Historique:
pubmed:
18
7
2019
medline:
11
7
2020
entrez:
18
7
2019
Statut:
ppublish
Résumé
The most common type of dementia is an Alzheimer's disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood. This study aims to evaluate the effects of blood biochemistry on Alzheimer's disease. Eight participants aged 55+ with Alzheimer's disease were analyzed. A cross-sectional work has conducted. Eighty patients have been divided into 2 groups as group A and group B according to laboratory findings including glycosylated hemoglobin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGA), vitamin D, folic acid, and vitamin B High levels of HDL, vitamin D, and folic acid correlate with cognitive scores, whereas high levels of total cholesterol, HbA1c, LDL show a negative effect on cognition scores. High-density lipoprotein, vitamin D, folic acid, cholesterol, HgA1c, and LDL have an effect on dementia.
Sections du résumé
BACKGROUND
The most common type of dementia is an Alzheimer's disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood.
OBJECTIVE
This study aims to evaluate the effects of blood biochemistry on Alzheimer's disease.
METHOD
Eight participants aged 55+ with Alzheimer's disease were analyzed. A cross-sectional work has conducted. Eighty patients have been divided into 2 groups as group A and group B according to laboratory findings including glycosylated hemoglobin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGA), vitamin D, folic acid, and vitamin B
RESULTS
High levels of HDL, vitamin D, and folic acid correlate with cognitive scores, whereas high levels of total cholesterol, HbA1c, LDL show a negative effect on cognition scores.
CONCLUSION
High-density lipoprotein, vitamin D, folic acid, cholesterol, HgA1c, and LDL have an effect on dementia.
Identifiants
pubmed: 31311283
doi: 10.1177/1533317519862108
doi:
Substances chimiques
Cholesterol, HDL
0
Cholesterol, LDL
0
Glycated Hemoglobin A
0
hemoglobin A1c protein, human
0
Vitamin D
1406-16-2
Folic Acid
935E97BOY8
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM