The Significance and Reliability of Imaging Findings in Pseudotumor Cerebri.
Intracranial hypertension
MRI
optic nerve
partial empty sella
Journal
Neuro-ophthalmology (Aeolus Press)
ISSN: 0165-8107
Titre abrégé: Neuroophthalmology
Pays: England
ID NLM: 8408966
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
22
05
2018
revised:
20
06
2018
accepted:
22
06
2018
pmc-release:
19
07
2019
entrez:
18
7
2019
pubmed:
18
7
2019
medline:
18
7
2019
Statut:
epublish
Résumé
The objective of our study was to provide a comparative assessment of previously reported magnetic resonance imaging (MRI) parameters in primary and secondary pseudotumor cerebri (PTC) patients, to examine their diagnostic contribution, and to evaluate their association with symptoms, neuro-ophthalmological findings, laboratory results, and cerebrospinal fluid characteristics. Twenty-eight consecutive patients with PTC were included in the study. Age- and sex-matched 20 individuals with normal neurologic examination served as the control group. Modified Dandy Criteria were used for the diagnosis of PTC. Orbital and cranial MRI and MR venography of all patients and controls were assessed by three radiologists. According to our study, posterior flattening of the globe (64% sensitive, 100% specific), optic nerve sheath distention (46% sensitive, 100% specific), vertical tortuosity of the optic nerve (30% sensitive, 95% specific), and partial empty sella (43% sensitive, 100% specific) emerged as particularly valuable markers for a diagnosis of PTC.
Identifiants
pubmed: 31312231
doi: 10.1080/01658107.2018.1493514
pii: 1493514
pmc: PMC6619944
doi:
Types de publication
Journal Article
Langues
eng
Pagination
81-90Références
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