Preoperative Evaluation and Management of Patients Receiving Biologic Therapies.
B cell inhibitor
Biologic therapy
Preoperative care
T cell inhibitor
TNF-α inhibitor
Journal
The archives of bone and joint surgery
ISSN: 2345-4644
Titre abrégé: Arch Bone Jt Surg
Pays: Iran
ID NLM: 101636743
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
entrez:
18
7
2019
pubmed:
18
7
2019
medline:
18
7
2019
Statut:
ppublish
Résumé
The preoperative care of patients undergoing orthopedic surgery and treated with biologic agents is of great significance. Perioperative use of biologic agents could lead to such complications as infection and delayed postoperative wound healing. This narrative review aimed to evaluate the current information on the use of biologic agents in patients undergoing orthopedic surgery, determine the rate of associated postoperative complications, and identify the appropriate time for the continuation or discontinuation of biologic therapy in these patients. It can be stated that all biologic agents increase the risk of infections depending on their half-lives. Biologic agents are suggested to be withheld for at least twice their half-lives before major surgeries. However, in case of minor operations, they can be continued given the low risk of infection and impaired wound healing in these cases. I.
Types de publication
Journal Article
Review
Langues
eng
Pagination
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