Plasminogen and the Plasminogen Receptor, Plg-R


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2019
Historique:
received: 07 03 2019
accepted: 10 06 2019
entrez: 19 7 2019
pubmed: 19 7 2019
medline: 22 10 2020
Statut: epublish

Résumé

Inflammation resolution is an active process that functions to restore tissue homeostasis. Clearance of apoptotic leukocytes by efferocytosis at inflammatory sites plays an important role in inflammation resolution and induces remarkable macrophage phenotypic and functional changes. Here, we investigated the effects of deletion of either plasminogen (Plg) or the Plg receptor, Plg-R

Identifiants

pubmed: 31316511
doi: 10.3389/fimmu.2019.01458
pmc: PMC6611080
doi:

Substances chimiques

PLG-R(KT) protein, mouse 0
Receptors, Cell Surface 0
Plasminogen 9001-91-6

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1458

Subventions

Organisme : BLRD VA
ID : I01 BX003933
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL081046
Pays : United States

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Auteurs

Juliana P Vago (JP)

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.
Center for Drug Research and Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Michelle A Sugimoto (MA)

Center for Drug Research and Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Barts and The London School of Medicine, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.

Kátia M Lima (KM)

Department of Clinical and Toxicological Analyses, School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Graziele L Negreiros-Lima (GL)

Department of Clinical and Toxicological Analyses, School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Nagyung Baik (N)

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.

Mauro M Teixeira (MM)

Center for Drug Research and Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Mauro Perretti (M)

Barts and The London School of Medicine, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.

Robert J Parmer (RJ)

Department of Medicine, Veterans Administration San Diego Healthcare System, University of California, San Diego, San Diego, CA, United States.

Lindsey A Miles (LA)

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.

Lirlândia P Sousa (LP)

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.
Center for Drug Research and Development, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Department of Clinical and Toxicological Analyses, School of Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Brazil.

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Classifications MeSH