Pituitary adenylate cyclase activating polypeptide acts against neovascularization in retinal pigment epithelial cells.
ARPE-19 cells
PACAP
VEGF
hyperosmosis
oxidative stress
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
21
02
2019
revised:
30
05
2019
accepted:
14
06
2019
pubmed:
19
7
2019
medline:
6
5
2020
entrez:
19
7
2019
Statut:
ppublish
Résumé
The purpose of this study was to determine whether pituitary adenylate cyclase activating polypeptide (PACAP) could influence the neovascularization processes in hyperosmotic and oxidative stress in retinal pigment epithelial cells. Hyperosmotic conditions and oxidative stress were induced by 200 mM sucrose and 250 µM hydrogen peroxide (H
Substances chimiques
Pituitary Adenylate Cyclase-Activating Polypeptide
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
160-172Subventions
Organisme : National Research Development and Innovation Office
ID : OTKA K-116158
Pays : International
Organisme : National Research Development and Innovation Office
ID : GINOP-2.3.2-15-2016-00020
Pays : International
Organisme : National Research Development and Innovation Office
ID : GINOP-2.3.3-15-2016-00030,
Pays : International
Organisme : National Research Development and Innovation Office
ID : GINOP-2.3.2-15-2016-00034
Pays : International
Organisme : János Bolyai Research Fellowship of the Hungarian Academy of Sciences
ID : BO/00334/16/8
Pays : International
Organisme : EFOP
Pays : International
Organisme : Magyar Tudományos Akadémia
ID : TKI14016
Pays : International
Organisme : ÚNKP
Pays : International
Organisme : Bolyai Foundation
ID : BO/00334/16/8
Pays : International
Organisme : NKP
Pays : International
Organisme : PTE-AOK
Pays : International
Informations de copyright
© 2019 New York Academy of Sciences.
Références
Bauer, H.C., A. Traweger, J. Zweimueller-Mayer, et al. 2011. New aspects of the molecular constituents of tissue barriers. J. Neural Transm. 118: 7-21.
Wilhelm, I., A.E. Farkas, P. Nagyoszi, et al. 2007. Regulation of cerebral endothelial cell morphology by extracellular calcium. Phys. Med. Biol. 52: 6261-6274.
Xu, H.Z. & Y.Z. Le. 2011. Significance of outer blood-retina barrier breakdown in diabetes and ischemia. Invest. Ophthalmol. Vis. Sci. 52: 2160-2164.
Willermain, F., S. Janssens, T. Arsenijevic, et al. 2014. Osmotic stress decreases aquaporin-4 expression in the human retinal pigment epithelial cell line, ARPE-19. Int. J. Mol. Med. 34: 533-538.
Veltmann, M., M. Hollborn, A. Reichenbach, et al. 2016. Osmotic induction of angiogenic growth factor expression in human retinal pigment epithelial cells. PLoS One 11: e0147312.
Strauss, O. 2005. The retinal pigment epithelium in visual function. Physiol. Rev. 85: 845-881.
Adamis, A.P., D.T. Shima, K.T. Yeo, et al. 1993. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 193: 631-638.
Lu, M., M. Kuroki, S. Amano, et al. 1998. Advanced glycation end products increase retinal vascular endothelial growth factor expression. J. Clin. Invest. 101: 1219-1224.
Lopez, P.F., B.D. Sippy, H.M. Lambert, et al. 1996. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Invest. Ophthalmol. Vis. Sci. 37: 855-868.
Simó, R., E. Carrasco, M. García-Ramírez & C. Hernández. 2006. Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy. Curr. Diabetes Rev. 2: 71-98.
Wirostko, B., T.Y. Wong & R. Simó. 2008. Vascular endothelial growth factor and diabetic complications. Prog. Retin. Eye Res. 27: 608-621.
Witmer, A.N., G.F. Vrensen, C.J. Van Noorden & R.O. Schlingemann. 2003. Vascular endothelial growth factors and angiogenesis in eye disease. Prog. Retin. Eye Res. 22: 1-29.
Burns, M.S. & M.J. Hartz. 1992. The retinal pigment epithelium induces fenestration of endothelial cells in vivo. Curr. Eye Res. 11: 863-873.
Pascolini, D. & S.P. Mariotti. 2012. Global estimates of visual impairment: 2010. Br. J. Ophthalmol. 96: 614-618.
Joussen, A.M., N. Smyth & C. Niessen. 2007. Pathophysiology of diabetic macular edema. Rev. Dev. Ophthalmol. 39: 1-12.
Onali, P. & M.C. Olianas. 1994. PACAP is a potent and highly effective stimulator of adenylyl cyclase activity in the retinas of different mammalian species. Brain Res. 241: 132-134.
Wang, Z.Y., P. Alm & R. Håkanson. 1995. Distribution and effects of pituitary adenylate cyclase-activating peptide in the rabbit eye. Neuroscience 69: 297-308.
Atlasz, T., A. Vaczy & D. Werling, et al. 2016. Chapter 30: Protective effects of PACAP in the retina. In Pituitary Adenylate Cyclase Activating Polypeptide-PACAP. D. Reglodi & A. Tamas, Eds.: 433-448. Springer.
Zhang, X.Y., S. Hayasaka, Z.L. Chi, et al. 2005. Effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on IL-6, IL-8, and MCP-1 expression in human retinal pigment epithelial cell line. Curr. Eye Res. 30: 1105-1111.
Mester, L., K. Kovács, B. Rácz, et al. 2011. Pituitary adenylate cyclase-activating polypeptide is protective against oxidative stress in human retinal pigment epithelial cells. J. Mol. Neurosci. 43: 35-43.
Fabian, E., D. Reglodi, L. Mester, et al. 2012. Effects of PACAP on intracellular signaling pathways in human retinal pigment epithelial cells exposed to oxidative stress. J. Mol. Neurosci. 48: 493-500.
Wilhelm, I. & I.A. Krizbai. 2016. Chapter 26: Effects of PACAP on biological barriers. In Pituitary Adenylate Cyclase Activating Polypeptide-PACAP. D. Reglodi & A. Tamas, Eds.: 433-448. Springer.
Wilhelm, I., C. Fazakas, A. Tamás, et al. 2014. PACAP enhances barrier properties of cerebral microvessels. J. Mol. Neurosci. 54: 469-476.
Scuderi, S., A.G. D'Amico, A. Castorina, et al. 2013. Ameliorative effect of PACAP and VIP against increased permeability in a model of outer blood retinal barrier dysfunction. Peptides 39: 119-124.
Jozsa, R., T. Hollosy, A. Tamas, et al. 2005. Pituitary adenylate cyclase activating polypeptide plays a role in olfactory memory formation in chicken. Peptides 26: 2344-2350.
Hutter, J.L. & J. Bechhoefer. 1993. Calibration of atomic-force microscope tips. Rev. Sci. Instrum. 64: 1868-1873.
Higgins, M.J., R. Proksch, J.E. Sader, et al. 2006. Noninvasive determination of optical lever sensitivity in atomic force microscopy. Rev. Sci. Instrum. 77: 013701.
Sader, J.E., J.A. Sanelli, B.D. Adamson, et al. 2012. Spring constant calibration of atomic force microscope cantilevers of arbitrary shape. Rev. Sci. Instrum. 83: 103705.
Varga, B., R.A. Domokos, C. Fazakas, et al. 2018. Deadhesion dynamics of melanoma cells from brain endothelial layer. Biochim. Biophys. Acta 1862: 745-751.
Desjardins, D.M., P.W. Yates, M. Dahrouj, et al. 2016. Progressive early breakdown of retinal pigment epithelium function in hyperglycemic rats. Invest. Ophthalmol. Vis. Sci. 57: 2706-2713.
Willermain, F., S. Libert, E. Motulsky, et al. 2014. Origins and consequences of hyperosmolar stress in retinal pigmented epithelial cells. Front. Physiol. 5: 199.
Plafker, S.M., G.B. O'Mealey & L.I. Szweda. 2012. Mechanisms for countering oxidative stress and damage in retinal pigment epithelium. Int. Rev. Cell Mol. Biol. 298: 135-177.
Torre, B., D. Ricci & P.C. Braga. 2011. How the atomic force microscope works? Methods Mol. Biol. 736: 3-18.
Varga, B., C. Fazakas, I. Wilhelm, et al. 2016. Elastomechanical properties of living cells. Biochem. Biophys. Rep. 7: 303-308.
Végh, A.G., C. Fazakas, K. Nagy, et al. 2011. Spatial and temporal dependence of the cerebral endothelial cells elasticity. J. Mol. Recognit. 24: 422-428.
Farkas, A., E. Szatmári, A. Orbók, et al. 2005. Hyperosmotic mannitol induces Src kinase-dependent phosphorylation of beta-catenin in cerebral endothelial cells. J. Neurosci. Res. 80: 855-861.
Balint, Z., I.A. Krizbai, I. Wilhelm, et al. 2007. Changes induced by hyperosmotic mannitol in cerebral endothelial cells: an atomic force microscopic study. Eur. Biophys. J. 36: 113-120.
Solymar, M., I. Ivic, M. Balasko, et al. 2018. Pituitary adenylate cyclase-activating polypeptide ameliorates vascular dysfunction induced by hyperglycaemia. Diab. Vasc. Dis. Res. 15: 277-285.
Hoeben, A., B. Landuyt, M.S. Highley, et al. 2004. Vascular endothelial growth factor and angiogenesis. Pharmacol. Rev. 56: 549-580.
Moody, T.W., J. Leyton, M. Casibang, et al. 2002. PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells. Regul. Pep. 109: 135-140.
Collado, B., I. Gutiérrez-Cañas, N. Rodríguez-Henche, et al. 2004. Vasoactive intestinal peptide increases vascular endothelial growth factor expression and neuroendocrine differentiation in human prostate cancer LNCaP cells. Regul. Pep. 119: 69-75.
Collado, B., M.G. Sánchez, I. Díaz-Laviada, et al. 2005. Vasoactive intestinal peptide (VIP) induces c-fos expression in LNCaP prostate cancer cells through a mechanism that involves Ca2+ signalling. Implications in angiogenesis and neuroendocrine differentiation. Biochim. Biophys. Acta 1744: 224-233.
Kvarik, T., B. Mammel, D. Reglodi, et al. 2016. PACAP is protective in a rat model of retinopathy of prematurity. J. Mol. Neurosci. 60: 179-185.
D'Amico, A.G., G. Maugeri, D.M. Rasà, et al. 2017. Modulation of IL-1β and VEGF expression in rat diabetic retinopathy after PACAP administration. Peptides 97: 64-69.
Maugeri, G., A.G. D'Amico, S. Saccone, et al. 2017. PACAP and VIP inhibit HIF-1α-mediated VEGF expression in a model of diabetic macular edema. J. Cell. Physiol. 232: 1209-1215.
Szabadfi, K., A. Szabo & P. Kiss. 2014. PACAP promotes neuron survival in early experimental diabetic retinopathy. Neurochem. Int. 64: 84-91.
Szabadfi, K., E. Pinter, D. Reglodi & R. Gabriel. 2014. Neuropeptides, trophic factors, and other substances providing morphofunctional and metabolic protection in experimental models of diabetic retinopathy. Int. Rev. Cell Mol. Biol. 311: 1-121.
Szabadfi, K., D. Reglodi, A. Szabo, et al. 2016. Pituitary adenylate cyclase activating polypeptide, a potential therapeutic agent for diabetic retinopathy in rats: focus on the vertical information processing pathway. Neurotox. Res. 29: 432-446.