Exosomes and Their Role in Cancer Progression.
cancer progression
exosome
extracellular vesicle
Journal
Yonago acta medica
ISSN: 0513-5710
Titre abrégé: Yonago Acta Med
Pays: Japan
ID NLM: 0414002
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
18
03
2019
accepted:
28
03
2019
entrez:
20
7
2019
pubmed:
20
7
2019
medline:
20
7
2019
Statut:
epublish
Résumé
Exosomes are a subset of extracellular vesicles and their size is approximately 100 nm in diameter. They are surrounded by a lipid bilayer membrane and secreted from almost all of cells. Exosomes are generated within the endocytic system as ILV (intraluminal membrane vesicle) and secreted during the fusion of MVB (multivesicular body) with the cell membrane. Recently it has been reported that exosomes modulate cell-cell communication contributing to the maintenance of tissue homeostasis by molecules including exosomes. Moreover, exosomes released from cancer cells are involved in cancer progression. Thus, data regarding the role of the exosomes in malignant cancer will lead to development of novel diagnostic and therapeutic methods.
Identifiants
pubmed: 31320822
doi: 10.33160/yam.2019.06.002
pii: 2019.06.002
pmc: PMC6584259
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
182-190Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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