The management and referral of iliofemoral deep venous thrombosis in North West London.


Journal

Journal of vascular surgery. Venous and lymphatic disorders
ISSN: 2213-3348
Titre abrégé: J Vasc Surg Venous Lymphat Disord
Pays: United States
ID NLM: 101607771

Informations de publication

Date de publication:
03 2020
Historique:
received: 10 01 2019
accepted: 11 04 2019
pubmed: 23 7 2019
medline: 15 9 2020
entrez: 23 7 2019
Statut: ppublish

Résumé

Post-thrombotic syndrome is a common complication of iliofemoral deep venous thrombosis (IFDVT). Existing evidence and National Institute for Health and Care Excellence guidelines suggest that this can be reduced by prompt thrombolytic therapy or thrombectomy. We aimed to evaluate the characteristics of IFDVT patients and to identify whether patients are being offered the recommended treatment pathway. A multicenter cross-sectional study was conducted across eight hospital sites in the North West London region, of which two were hub hospitals in their local vascular service networks. Patients with proximal DVT were identified using International Classification of Diseases, Tenth Revision coding during a 1-year period. Data on demographics, diagnostic methods used, interventions, and referrals were extracted from electronic and paper medical records. During the study period, 132 patients with IFDVT were identified (mean age, 59.4 years; 55% female); 75% of these patients had an IFDVT. In this cohort, the biggest predisposing factors were previous DVT (n = 35), malignant disease (n = 35), and immobility (n = 20). In total, 104 patients were administered anticoagulation, and 88 of these patients received anticoagulation within 24 hours. The cases of 45 patients were either discussed with or promptly referred to a vascular service, after which 20 patients were treated solely with anticoagulation, whereas 20 patients received thrombolysis of varying methods. A significant proportion (56%) of symptomatic IFDVT patients are not being appropriately referred to or discussed with vascular services. Of these, 43% would have been eligible for consideration of early thrombus removal. Adherence to the National Institute for Health and Care Excellence guidelines could be improved by increasing awareness among emergency department colleagues.

Sections du résumé

BACKGROUND
Post-thrombotic syndrome is a common complication of iliofemoral deep venous thrombosis (IFDVT). Existing evidence and National Institute for Health and Care Excellence guidelines suggest that this can be reduced by prompt thrombolytic therapy or thrombectomy. We aimed to evaluate the characteristics of IFDVT patients and to identify whether patients are being offered the recommended treatment pathway.
METHODS
A multicenter cross-sectional study was conducted across eight hospital sites in the North West London region, of which two were hub hospitals in their local vascular service networks. Patients with proximal DVT were identified using International Classification of Diseases, Tenth Revision coding during a 1-year period. Data on demographics, diagnostic methods used, interventions, and referrals were extracted from electronic and paper medical records.
RESULTS
During the study period, 132 patients with IFDVT were identified (mean age, 59.4 years; 55% female); 75% of these patients had an IFDVT. In this cohort, the biggest predisposing factors were previous DVT (n = 35), malignant disease (n = 35), and immobility (n = 20). In total, 104 patients were administered anticoagulation, and 88 of these patients received anticoagulation within 24 hours. The cases of 45 patients were either discussed with or promptly referred to a vascular service, after which 20 patients were treated solely with anticoagulation, whereas 20 patients received thrombolysis of varying methods.
CONCLUSIONS
A significant proportion (56%) of symptomatic IFDVT patients are not being appropriately referred to or discussed with vascular services. Of these, 43% would have been eligible for consideration of early thrombus removal. Adherence to the National Institute for Health and Care Excellence guidelines could be improved by increasing awareness among emergency department colleagues.

Identifiants

pubmed: 31327742
pii: S2213-333X(19)30316-6
doi: 10.1016/j.jvsv.2019.04.011
pii:
doi:

Substances chimiques

Anticoagulants 0

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

182-186

Informations de copyright

Copyright © 2019 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Auteurs

Kaywaan Khan (K)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom. Electronic address: kaywaan@googlemail.com.

Mimi Li (M)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Simon Erridge (S)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Swathikan Chidambaram (S)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Kayla Chiew (K)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Leon Pay (L)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Ross Goodson (R)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Clifford Lek (C)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Nikhil Math (N)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Joanna Wong (J)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Srishti Chhabra (S)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Apichaya Amrapala (A)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Husein Rajabali (H)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Saniya Mediratta (S)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Kristi Sun (K)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

James Bryan (J)

Imperial College Surgical Society, Imperial College School of Medicine, London, United Kingdom; Faculty of Medicine, Imperial College London, London, United Kingdom.

Andrew Busuttil (A)

Section of Vascular Surgery, Imperial College London, London, United Kingdom.

Alun H Davies (AH)

Section of Vascular Surgery, Imperial College London, London, United Kingdom.

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Classifications MeSH