Head and neck cancer during pregnancy.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
10 2019
Historique:
received: 14 03 2019
revised: 28 06 2019
accepted: 03 07 2019
pubmed: 23 7 2019
medline: 12 9 2020
entrez: 23 7 2019
Statut: ppublish

Résumé

The incidence of cancer during pregnancy is low but is slightly increasing. Data on incidence and etiology of head and neck (HN) cancers in pregnant women are rare. We evaluated the frequency, tumor type, associated factors, and specific biomarkers in HN cancers occurring in pregnant (and peripartum) women. A systematic literature search was performed on PubMed, for any HN tumor site occurring in pregnant women. Sixty cases of HN cancers occurring during pregnancy were identified. Most of them were oral cavity cancers. Relationships with oncogenic viruses, hormonal disturbance, and shift in maternal immunity profile were identified. Carcinogenesis of HN cancers in pregnant women may be led by different cancer type-specific hallmarks. Relevance of these etiological factors with respect to treatments and birth control recommendations is being investigated by the REFCOR in an ambispective study.

Sections du résumé

BACKGROUND
The incidence of cancer during pregnancy is low but is slightly increasing. Data on incidence and etiology of head and neck (HN) cancers in pregnant women are rare. We evaluated the frequency, tumor type, associated factors, and specific biomarkers in HN cancers occurring in pregnant (and peripartum) women.
METHODS
A systematic literature search was performed on PubMed, for any HN tumor site occurring in pregnant women.
RESULTS
Sixty cases of HN cancers occurring during pregnancy were identified. Most of them were oral cavity cancers. Relationships with oncogenic viruses, hormonal disturbance, and shift in maternal immunity profile were identified.
CONCLUSION
Carcinogenesis of HN cancers in pregnant women may be led by different cancer type-specific hallmarks. Relevance of these etiological factors with respect to treatments and birth control recommendations is being investigated by the REFCOR in an ambispective study.

Identifiants

pubmed: 31329334
doi: 10.1002/hed.25877
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3719-3732

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Références

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Auteurs

Jennifer Le Guevelou (J)

Service de Radiothérapie, Centre François Baclesse, Caen, France.

Sabrina Lebars (S)

Bureau CORASSO, France.

Emmanuel Kammerer (E)

Service de Radiothérapie, Centre François Baclesse, Caen, France.

Ludovic de Gabory (L)

Service de Chirurgie ORL, Centre Hospitalier Universitaire Pellegrin, Bordeaux, France.

Sebastien Vergez (S)

Service de Chirurgie ORL, Centre Hospitalier Universitaire Rangueil-Larrey, Toulouse, France.

François Janot (F)

Service de Chirurgie ORL, Centre Gustave Roussy, Villejuif, France.

Bertrand Baujat (B)

Service de Chirurgie ORL, Hopital Tenon, Université Paris-Est, Paris, France.

Christian Righini (C)

Service de Chirurgie ORL, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.

Franck Jegoux (F)

Service de Chirurgie ORL, Centre Hospitalier Universitaire Pontchaillou, Rennes, France.

Xavier Dufour (X)

Service de Chirurgie ORL, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.

Jean-Claude Merol (JC)

Service de Chirurgie ORL, Centre Hospitalier Universitaire de Reims, Reims, France.

Olivier Mauvais (O)

Service de Chirurgie ORL, Centre Hospitalier Universitaire de Besançon, Besançon, France.

Audrey Lasne-Cardon (A)

Service de Chirurgie ORL Centre François Baclesse, Normandie Université-Unicaen, Caen, France.

Lise Selleret (L)

Service de Gynécologie Obstetrique, Hopital Tenon, Paris, France.

Juliette Thariat (J)

Service de Radiothérapie, Centre François Baclesse, Caen, France.

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