Older adults exhibit a more pronounced modulation of beta oscillations when performing sustained and dynamic handgrips.
Aging
Beta oscillations
Handgrips
MEG
Motor control
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 11 2019
01 11 2019
Historique:
received:
01
04
2019
revised:
12
07
2019
accepted:
19
07
2019
pubmed:
23
7
2019
medline:
8
5
2020
entrez:
23
7
2019
Statut:
ppublish
Résumé
Muscle contractions are associated with a decrease in beta oscillatory activity, known as movement-related beta desynchronization (MRBD). Older adults exhibit a MRBD of greater amplitude compared to their younger counterparts, even though their beta power remains higher both at rest and during muscle contractions. Further, a modulation in MRBD has been observed during sustained and dynamic pinch contractions, whereby beta activity during periods of steady contraction following a dynamic contraction is elevated. However, how the modulation of MRBD is affected by aging has remained an open question. In the present work, we investigated the effect of aging on the modulation of beta oscillations and their putative link with motor performance. We collected magnetoencephalography (MEG) data from younger and older adults during a resting-state period and motor handgrip paradigms, which included sustained and dynamic contractions, to quantify spontaneous and motor-related beta oscillatory activity. Beta power at rest was found to be significantly increased in the motor cortex of older adults. During dynamic hand contractions, MRBD was more pronounced in older participants in frontal, premotor and motor brain regions. These brain areas also exhibited age-related decreases in cortical thickness; however, the magnitude of MRBD and cortical thickness were not found to be associated after controlling for age. During sustained hand contractions, MRBD exhibited a decrease in magnitude compared to dynamic contraction periods in both groups and did not show age-related differences. This suggests that the amplitude change in MRBD between dynamic and sustained contractions is larger in older compared to younger adults. We further probed for a relationship between beta oscillations and motor behaviour and found that greater MRBD in primary motor cortices was related to degraded motor performance beyond age, but our results suggested that age-related differences in beta oscillations were not predictive of motor performance.
Identifiants
pubmed: 31330245
pii: S1053-8119(19)30618-4
doi: 10.1016/j.neuroimage.2019.116037
pmc: PMC6765431
mid: NIHMS1536094
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
116037Subventions
Organisme : NIBIB NIH HHS
ID : R01 EB009048
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB026299
Pays : United States
Informations de copyright
Crown Copyright © 2019. Published by Elsevier Inc. All rights reserved.
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