Female fertility preservation in DSD.

Adolescent Cryopreservation Disorders of Sex Development / physiopathology Female Fertility Preservation Humans Oocytes Turner Syndrome / physiopathology
DSD fertility preservation gonadotoxic therapy turner syndrome

Journal

Best practice & research. Clinical endocrinology & metabolism
ISSN: 1878-1594
Titre abrégé: Best Pract Res Clin Endocrinol Metab
Pays: Netherlands
ID NLM: 101120682

Informations de publication

Date de publication:
06 2019
Historique:
pubmed: 25 7 2019
medline: 18 2 2020
entrez: 24 7 2019
Statut: ppublish

Résumé

Disorders of sex development (DSD) are a group of complex conditions that can affect chromosomal, gonadal, and/or phenotypical sex with a highly variable fertility potential amongst affected individuals. In this review we discuss fertility issues facing patients affected by DSD and Turner syndrome and summarise the literature on fertility and reproductive outcomes. We will also discuss fertility preservation prior to gonadotoxic treatment in adolescent and prepubertal girls. Future directions in fertility preservation and ethical issues will also be addressed. Fertility preserving options that are established include ovarian tissue and oocyte cryopreservation. However, in many of the DSDs fertility is not possible and the discussion may need to move toward alternative methods of creating a family such as gamete donation or surrogacy.

Identifiants

DOI: 10.1016/j.beem.2019.101289 PMID: 31331728
pubmed: 31331728
pii: S1521-690X(19)30040-5
doi: 10.1016/j.beem.2019.101289
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101289

Informations de copyright

Copyright © 2019. Published by Elsevier Ltd.

Auteurs

Rashi Kalra (R)

Reproductive Services Unit, The Royal Women's Hospital, Parkville VIC 3052, Australia. Electronic address: rashi.kalra2@thewomens.org.au.

Melissa Cameron (M)

Department of Obstetrics and Gynaecology, University of Melbourne, The Royal Women's Hospital, Parkville, VIC 3052, Australia.

Catharyn Stern (C)

Department of Obstetrics and Gynaecology, University of Melbourne, The Royal Women's Hospital, Parkville, VIC 3052, Australia.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Female fertility preservation in DSD.
questionsmedicales.fr › Techniques d'investigation › Conservation biologique › Cryoconservation › Female fertility preservation in DSD.
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Troubles du développement sexuel › Female fertility preservation in DSD.
questionsmedicales.fr › Techniques d'investigation › Techniques de reproduction › Techniques de reproduction assistée › Préservation de la fertilité › Female fertility preservation in DSD.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Female fertility preservation in DSD.
questionsmedicales.fr › Cellules › Cellules germinales › Ovocytes › Female fertility preservation in DSD.
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Troubles du développement sexuel › Troubles du développement sexuel avec anomalie des gonosomes › Syndrome de Turner › Female fertility preservation in DSD.