Intra-arterial chemotherapy for retinoblastoma: the dosimetric impact.
Absorbed dose
Dose exposition
Intra-arterial chemotherapy
Radiation parameters
Retinoblastoma
Journal
Neuroradiology
ISSN: 1432-1920
Titre abrégé: Neuroradiology
Pays: Germany
ID NLM: 1302751
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
08
05
2019
accepted:
05
07
2019
pubmed:
25
7
2019
medline:
6
2
2020
entrez:
24
7
2019
Statut:
ppublish
Résumé
Purposes are (1) to measure main radiation parameters and (2) to propose a method to estimate the absorbed doses of internal organs starting from DAP values. Measuring the exposition of internal organs by repeated irradiations on an anthropomorphic phantom with the same settings used in vivo, we could establish correlations between (1) DAP and the dose recorded by a dosimeter placed along the X-ray beam entrance pathway; (2) the dose recorded by the same dosimeter and the absorbed dose in internal organs. Forty-four consecutive patients (16 males, 28 females) (mean age 35.4 months) treated at our institution with IAC (216 procedures: 196 via the ICA and 20 into branches of the ECA) were included in this prospective study. IAC was divided into 5 phases. Fluoroscopic time, DAP, and ESD were measured. The mean DAP was 595 ± 445 cGy cm This paper describes a method of absorbed dose estimation providing ranges used clinically in a single practice and the basis for further prospective studies.
Identifiants
pubmed: 31332478
doi: 10.1007/s00234-019-02260-7
pii: 10.1007/s00234-019-02260-7
doi:
Substances chimiques
Antineoplastic Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1083-1091Références
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