Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence.

Flavopereirine P53 colorectal cancer

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
22 Jul 2019
Historique:
received: 10 06 2019
revised: 17 07 2019
accepted: 19 07 2019
entrez: 25 7 2019
pubmed: 25 7 2019
medline: 25 7 2019
Statut: epublish

Résumé

Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. The outcome of CRC patients remains poor. Thus, a new strategy for CRC treatment is urgently needed. Flavopereirine is a β-carboline alkaloid extracted from

Identifiants

pubmed: 31336690
pii: cancers11071034
doi: 10.3390/cancers11071034
pmc: PMC6678721
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Chang Gung Memorial Hospital
ID : CMRPG6F0581-3
Organisme : Chang Gung Memorial Hospital
ID : CMRPG6G0291
Organisme : Ministry of Science and Technology
ID : MOST103-2314-B-182A-105
Organisme : Ministry of Science and Technology
ID : MOST105-2314-B-182A-096

Références

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2147-52
pubmed: 10051609
Semin Cancer Biol. 1998;8(5):345-57
pubmed: 10101800
Nature. 2000 Nov 16;408(6810):307-10
pubmed: 11099028
Curr Opin Cell Biol. 2001 Apr;13(2):211-7
pubmed: 11248555
Oncogene. 2001 May 28;20(24):3021-7
pubmed: 11420717
Cancer Res. 2002 May 1;62(9):2644-9
pubmed: 11980662
J Clin Invest. 2002 May;109(9):1133-7
pubmed: 11994400
Oncogene. 2002 Dec 5;21(55):8404-13
pubmed: 12466961
Mol Cell. 2003 Mar;11(3):577-90
pubmed: 12667443
Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8354-9
pubmed: 12821781
Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7491-5
pubmed: 1323840
Mol Cancer Res. 2003 Dec;1(14):1001-8
pubmed: 14707283
Clin Cancer Res. 2004 Mar 15;10(6):2158-67
pubmed: 15041737
Nat Med. 2004 Dec;10(12):1321-8
pubmed: 15558054
Cell. 2005 Oct 7;123(1):49-63
pubmed: 16213212
J Gastroenterol. 2006 Mar;41(3):185-92
pubmed: 16699851
Thromb Res. 2007;119(6):769-75
pubmed: 16844201
Nat Rev Immunol. 2007 Jan;7(1):41-51
pubmed: 17186030
Urology. 2009 Jan;73(1):188-92
pubmed: 18692879
N Engl J Med. 2008 Oct 23;359(17):1757-65
pubmed: 18946061
Cancer Res. 1991 Dec 1;51(23 Pt 1):6304-11
pubmed: 1933891
Cancer Cell. 2009 May 5;15(5):441-53
pubmed: 19411072
Ann Surg Oncol. 2010 Apr;17(4):1168-76
pubmed: 19936839
Annu Rev Pathol. 2011;6:479-507
pubmed: 21090969
Int J Oncol. 1994 Oct;5(4):873-9
pubmed: 21559655
Epigenetics. 2011 Sep 1;6(9):1068-77
pubmed: 21814038
Clin Cancer Res. 2012 Jan 1;18(1):290-300
pubmed: 22090360
Mol Carcinog. 2013 Feb;52(2):155-66
pubmed: 22121102
Small GTPases. 2012 Jan-Mar;3(1):34-9
pubmed: 22714415
Int J Cancer. 2014 Feb 15;134(4):997-1007
pubmed: 23934972
Cancers (Basel). 2013 Jun 05;5(2):676-713
pubmed: 24216997
Lancet. 2014 Apr 26;383(9927):1490-1502
pubmed: 24225001
Biochim Biophys Acta. 2014 Apr;1845(2):136-54
pubmed: 24388873
World J Surg Oncol. 2014 May 21;12:155
pubmed: 24885967
Nucleic Acids Res. 2014 Jul;42(12):7666-80
pubmed: 24928858
Nat Rev Cancer. 2014 Nov;14(11):736-46
pubmed: 25342631
CA Cancer J Clin. 2015 Mar;65(2):87-108
pubmed: 25651787
World J Gastroenterol. 2015 Feb 14;21(6):1982-8
pubmed: 25684967
Genes Dis. 2015 Mar;2(1):4-12
pubmed: 25815366
J Gastrointest Oncol. 2015 Apr;6(2):185-200
pubmed: 25830038
Mol Cancer Ther. 2015 Oct;14(10):2260-9
pubmed: 26227489
Chem Biol. 2015 Sep 17;22(9):1206-16
pubmed: 26320861
Updates Surg. 2016 Mar;68(1):7-11
pubmed: 27067591
DNA Repair (Amst). 2016 Jun;42:63-71
pubmed: 27156098
Cold Spring Harb Perspect Med. 2016 Sep 01;6(9):null
pubmed: 27449973
Neoplasia. 2017 Apr;19(4):301-309
pubmed: 28284059
Oncol Lett. 2017 Apr;13(4):2089-2096
pubmed: 28454366
Signal Transduct Target Ther. 2017 Oct 27;2:17051
pubmed: 29263930
Front Pharmacol. 2018 Aug 22;9:958
pubmed: 30186180
Oncol Lett. 2018 Nov;16(5):5575-5582
pubmed: 30344711
Exp Cell Biol. 1982;50(2):79-87
pubmed: 7075859
Science. 1994 Apr 1;264(5155):95-8
pubmed: 8140422
Anticancer Res. 1993 Nov-Dec;13(6A):2301-8
pubmed: 8297150
Nature. 1993 Sep 2;365(6441):79-82
pubmed: 8361542
Nature. 1993 Apr 29;362(6423):847-9
pubmed: 8479522
Cell. 1996 Oct 18;87(2):159-70
pubmed: 8861899
FEBS Lett. 1997 Apr 14;406(3):234-42
pubmed: 9136893
Nature. 1997 May 15;387(6630):296-9
pubmed: 9153395
J Cell Physiol. 1997 Nov;173(2):247-55
pubmed: 9365531
Genes Dev. 1997 Dec 15;11(24):3471-81
pubmed: 9407038
Science. 1998 Sep 11;281(5383):1677-9
pubmed: 9733515
Int J Cancer. 1998 Oct 29;78(3):326-30
pubmed: 9766567

Auteurs

Jhy-Ming Li (JM)

Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.

Yun-Ching Huang (YC)

Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.

Yi-Hung Kuo (YH)

Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.

Chih-Chung Cheng (CC)

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.

Feng-Che Kuan (FC)

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Department of Hematology and Oncology, Department of Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.

Shun-Fu Chang (SF)

Department of Medical Research and Development, Chang Gung Memorial Hospital Chiayi Branch, Chiayi 61363, Taiwan.

Ying-Ray Lee (YR)

Department of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 60002, Taiwan.

Chih-Chien Chin (CC)

Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. ccchin@cgmh.org.tw.

Chung-Sheng Shi (CS)

Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. csshi@mail.cgu.edu.tw.
Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan. csshi@mail.cgu.edu.tw.
Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. csshi@mail.cgu.edu.tw.

Classifications MeSH