Augmentation of myocardial I

Animals Apoptosis Calcium / metabolism Cardiac Electrophysiology Gene Expression Profiling Heart / physiology Homeostasis Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels / genetics Mice, Transgenic Muscle Proteins / genetics Myocardium / metabolism Myocytes, Cardiac / metabolism Potassium Channels / genetics Troponin I / genetics

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
23 07 2019
Historique:
received: 19 06 2015
accepted: 28 06 2019
entrez: 25 7 2019
pubmed: 25 7 2019
medline: 6 2 2020
Statut: epublish

Résumé

HCN channels underlie the depolarizing funny current (I

Identifiants

DOI: 10.1038/s41467-019-11261-2 PMID: 31337768 PMC: PMC6650438
pubmed: 31337768
doi: 10.1038/s41467-019-11261-2
pii: 10.1038/s41467-019-11261-2
pmc: PMC6650438
doi:

Substances chimiques

HCN4 protein, human 0
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels 0
Muscle Proteins 0
Potassium Channels 0
Troponin I 0
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3295

Références

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Auteurs

Pessah Yampolsky (P)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Department of Molecular Neurology, Max-Planck-Institute for Medical Research, Jahnstrasse 29, 69120, Heidelberg, Germany.
ORCID: 0000-0003-1419-0741

Michael Koenen (M)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Department of Molecular Neurology, Max-Planck-Institute for Medical Research, Jahnstrasse 29, 69120, Heidelberg, Germany.

Matias Mosqueira (M)

Division of Medical Biophysics, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.
ORCID: 0000-0001-7744-9138

Pascal Geschwill (P)

Division of Neuro- and Sensory Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.

Sebastian Nauck (S)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Heidelberg/Mannheim, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
ORCID: 0000-0002-1216-9511

Monika Witzenberger (M)

Division of Medical Biophysics, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.
ORCID: 0000-0002-9576-3523

Claudia Seyler (C)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Heidelberg/Mannheim, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Thomas Fink (T)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Mathieu Kruska (M)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Claus Bruehl (C)

Division of Neuro- and Sensory Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.

Alexander P Schwoerer (AP)

Department of Cellular and Integrative Physiology, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Hamburg/Kiel/Lübeck, Martinistrasse 52, 20246, Hamburg, Germany.
ORCID: 0000-0002-6050-0045

Heimo Ehmke (H)

Department of Cellular and Integrative Physiology, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Hamburg/Kiel/Lübeck, Martinistrasse 52, 20246, Hamburg, Germany.
ORCID: 0000-0003-3465-7185

Rainer H A Fink (RHA)

Division of Medical Biophysics, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.

Andreas Draguhn (A)

Division of Neuro- and Sensory Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Im Neuenheimer Feld 326, 69120, Heidelberg, Germany.

Dierk Thomas (D)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Heidelberg/Mannheim, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Hugo A Katus (HA)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research) partner site Heidelberg/Mannheim, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Patrick A Schweizer (PA)

Department of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. patrick.schweizer@med.uni-heidelberg.de.
DZHK (German Centre for Cardiovascular Research) partner site Heidelberg/Mannheim, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. patrick.schweizer@med.uni-heidelberg.de.
ORCID: 0000-0002-7212-1202

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Augmentation of myocardial I
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Augmentation of myocardial I
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Augmentation of myocardial I
questionsmedicales.fr › Professions de santé › Médecine › Médecine interne › Cardiologie › Électrophysiologie cardiaque › Augmentation of myocardial I
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Augmentation of myocardial I
questionsmedicales.fr › Système cardiovasculaire › Coeur › Augmentation of myocardial I
questionsmedicales.fr › Phénomènes physiologiques › Homéostasie › Augmentation of myocardial I
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux contrôlés par les nucléotides cycliques et activés par l'hyperpolarisation › Augmentation of myocardial I
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Augmentation of myocardial I
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines contractiles › Protéines du muscle › Augmentation of myocardial I
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › Augmentation of myocardial I
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › Augmentation of myocardial I
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Augmentation of myocardial I
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines des microfilaments › Troponine › Troponine I › Augmentation of myocardial I