Identification of hepadnavirus in the sera of cats.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 07 2019
23 07 2019
Historique:
received:
01
02
2019
accepted:
12
07
2019
entrez:
25
7
2019
pubmed:
25
7
2019
medline:
24
10
2020
Statut:
epublish
Résumé
Hepadnaviruses infect several animal species. The prototype species, human hepatitis B virus (HBV), increases the risk of liver diseases and may cause cirrhosis and hepatocellular carcinoma. Recently a novel hepadnavirus, similar to HBV, has been identified through transcriptomics studies in a domestic cat with large cell lymphoma in Australia. Herewith, a collection of 390 feline serum samples was screened for hepadnavirus. Overall, the virus was identified in 10.8% of the sera with a significantly higher prevalence (17.8%) in the sera of animals with a clinical suspect of infectious disease. Upon genome sequencing, the virus was closely related (97.0% nt identity) to the prototype Australian feline virus Sydney 2016. The mean and median values of hepadnavirus in the feline sera were 1.3 × 10
Identifiants
pubmed: 31337847
doi: 10.1038/s41598-019-47175-8
pii: 10.1038/s41598-019-47175-8
pmc: PMC6650429
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
10668Références
Hepatology. 2009 Sep;50(3):661-2
pubmed: 19714720
Nucleic Acids Res. 2002 Jul 15;30(14):3059-66
pubmed: 12136088
Viruses. 2018 May 17;10(5):
pubmed: 29772771
J Virol Methods. 2010 Oct;169(1):176-80
pubmed: 20674611
Bioinformatics. 2001 Aug;17(8):754-5
pubmed: 11524383
J Feline Med Surg. 2015 Jul;17(7):588-93
pubmed: 26101310
Virol J. 2017 Feb 22;14(1):40
pubmed: 28222808
Hepatol Int. 2017 Nov;11(6):500-508
pubmed: 29098564
Emerg Infect Dis. 2018 Jun;24(6):1061-1068
pubmed: 29774829
Hepatology. 2018 Apr;67(4):1560-1599
pubmed: 29405329
Science. 1987 Feb 13;235(4790):790-3
pubmed: 3643650
Vet Microbiol. 2019 Jan;228:246-251
pubmed: 30593374
Vet Microbiol. 1988 Jul;17(3):287-96
pubmed: 2847393
Bioinformatics. 2003 Aug 12;19(12):1572-4
pubmed: 12912839
Vet Immunol Immunopathol. 1989 May;21(1):85-95
pubmed: 2549696
Viruses. 2012 Oct 31;4(11):2684-710
pubmed: 23202500
Vet Microbiol. 2017 Mar;201:14-17
pubmed: 28284600