Brodifacoum toxicosis and abortion in an Arabian mare.

Arabian horse Brodifacoum HPLC Hemato-biochemical Rodenticide

Journal

Veterinary research forum : an international quarterly journal
ISSN: 2008-8140
Titre abrégé: Vet Res Forum
Pays: Iran
ID NLM: 101625812

Informations de publication

Date de publication:
2019
Historique:
received: 06 05 2018
accepted: 25 09 2018
entrez: 25 7 2019
pubmed: 25 7 2019
medline: 25 7 2019
Statut: ppublish

Résumé

A 3-year-old pregnant Arabian mare was referred to the Veterinary Teaching Hospital of Shahid Chamran University of Ahvaz with a history of bleeding and rodenticide ingestion. The results of paraclinical examinations showed severe normocytic and normochromic anemia, decreased serum total protein, albumin, and fibrinogen concentrations, increased serum total bilirubin, urea, and creatinine concentrations, as well as increased serum aspartate aminotransferase and creatine kinase activity. Three days after treatment, all the clinical signs were resolved, however, fetus abortion occurred. In order to confirm the suspected cause of abortion and toxicosis, high-performance liquid chromatography was performed on serum sample of mare and liver tissue of the aborted fetus and toxicosis was confirmed. Poisoning with brodifacoum is considered as an important and lethal poisoning for both human being and animals. To our knowledge, this is the first report of spontaneous toxicosis and abortion with brodifacoum. Brodifacoum toxicosis can be effectively managed with early diagnosis, good paraclinical examinations and appropriate treatment.

Identifiants

pubmed: 31338153
doi: 10.30466/vrf.2018.85534.2115
pmc: PMC6626650
doi:

Types de publication

Case Reports

Langues

eng

Pagination

173-176

Déclaration de conflit d'intérêts

None of the authors has any conflict of interest in the present study.

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Auteurs

Amir Zakian (A)

Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.

Sajad Mami (S)

Department of Laboratory and Clinical Sciences, Faculty of Veterinary Medicine, Ilam University, Ilam, Iran.

Mohammad Nouri (M)

Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.

Seyedeh Misagh Jalali (SM)

Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.

Meysam Tehrani-Sharif (M)

Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran.

Classifications MeSH