Pediatric pulmonary mucormycosis in a diabetic patient treated with extended pleurectomy and Clagett procedure.
Clagett procedure
Diabetes
Mucormycosis
Pediatric thoracic surgery
Pneumonectomy
Pulmonary mucormycosis
Journal
Journal of pediatric surgery case reports
ISSN: 2213-5766
Titre abrégé: J Pediatr Surg Case Rep
Pays: Netherlands
ID NLM: 101628383
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
entrez:
26
7
2019
pubmed:
26
7
2019
medline:
26
7
2019
Statut:
ppublish
Résumé
Mucor is a ubiquitous fungus that is non-pathogenic in healthy people. In immunocompromised hosts, non-functional or absent neutrophils and macrophages result in fungal invasion and infection [1]. Invasive mucor (mucormycosis) most commonly involves the sinuses, brain, or lungs. Pulmonary mucormycosis typically presents in patients with a history of organ transplantation or hematologic malignancy [2], and is rare in patients with diabetes alone. The epidemiology and management of pediatric pulmonary mucormycosis is poorly described. We report an unusual occurrence of this disease, complicated by segmental pulmonary artery thrombus in a 15-year-old with poorly controlled diabetes. His severe, medication-resistant infection was ultimately treated successfully with antifungal medication combined with aggressive surgical debridement. The pulmonary artery segmental thrombus resolved after treatment of the underlying infection without anticoagulation.
Identifiants
pubmed: 31341773
doi: 10.1016/j.epsc.2019.101210
pmc: PMC6655502
mid: NIHMS1528961
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NIBIB NIH HHS
ID : R25 EB023856
Pays : United States
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