Mesenchymal stem cells promote mesenteric vasodilation through hydrogen sulfide and endothelial nitric oxide.
Adiponectin
/ metabolism
Animals
Arterioles
/ physiology
Cystathionine beta-Synthase
/ metabolism
Gene Knockdown Techniques
Humans
Hydrogen Sulfide
/ metabolism
In Vitro Techniques
Male
Mesenchymal Stem Cells
/ physiology
Mesenteric Ischemia
Mice
Mice, Inbred C57BL
Nitric Oxide Synthase Type III
/ metabolism
Resistin
/ metabolism
Splanchnic Circulation
/ physiology
Vasodilation
/ physiology
eNOS
hydrogen sulfide
mesenchymal stromal cells
mesenteric vessels
pressure myography
Journal
American journal of physiology. Gastrointestinal and liver physiology
ISSN: 1522-1547
Titre abrégé: Am J Physiol Gastrointest Liver Physiol
Pays: United States
ID NLM: 100901227
Informations de publication
Date de publication:
01 10 2019
01 10 2019
Historique:
pubmed:
26
7
2019
medline:
31
3
2020
entrez:
26
7
2019
Statut:
ppublish
Résumé
Mesenteric ischemia is a devastating process that can result in intestinal necrosis. Mesenchymal stem cells (MSCs) are becoming a promising treatment modality. We hypothesized that
Identifiants
pubmed: 31343254
doi: 10.1152/ajpgi.00132.2019
pmc: PMC6842994
doi:
Substances chimiques
Adiponectin
0
Adipoq protein, mouse
0
Resistin
0
Retn protein, mouse
0
Nitric Oxide Synthase Type III
EC 1.14.13.39
Nos3 protein, mouse
EC 1.14.13.39
Cystathionine beta-Synthase
EC 4.2.1.22
Hydrogen Sulfide
YY9FVM7NSN
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
G441-G446Subventions
Organisme : NIDDK NIH HHS
ID : K08 DK113226
Pays : United States
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