Ectopic ACTH Syndrome in a Child With Abdominal Ewing Sarcoma: A Rare Paraneoplastic Phenomenon.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
10 2020
Historique:
pubmed: 26 7 2019
medline: 1 1 2021
entrez: 26 7 2019
Statut: ppublish

Résumé

Ectopic adrenocorticotropic hormone syndrome is a paraneoplastic phenomenon rarely seen in pediatrics and rarely described in Ewing sarcoma. We report a 15-year-old boy with abdominal Ewing sarcoma and clinical and laboratory findings of ectopic adrenocorticotropic hormone syndrome that promptly resolved with treatment of the tumor.

Identifiants

pubmed: 31343485
doi: 10.1097/MPH.0000000000001569
pii: 00043426-202010000-00037
doi:

Substances chimiques

Adrenocorticotropic Hormone 9002-60-2

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e668-e669

Références

Sharma ST, Nieman LK, Feelders RA. Cushing’s disease: epidemiology and developments in management. Clin Epidemiol. 2015;7:281–293.
Savage MO, Chan LF, Afshar F, et al. Advances in the management of pediatric Cushing’s disease. Horm Res. 2008;69:327–333.
More J, Young J, Reznik Y, et al. Ectopic ACTH syndrome in children and adolescents. J Clin Endocrinol Metab. 2011;96:1213–1222.
Wang J, Zhang G. Paraneoplastic Cushing’s syndrome because of corticotropin-releasing hormone-secreting Wilm’s tumor. J Pediatr Surg. 2008;43:2099–2101.
Segers H, van der Heyden JC, van der Akker EL, et al. Cushing syndrome as a presenting symptom of renal tumors in children. Pediatr Blood Cancer. 2009;53:211–213.
Grunewald TG, von Luettrichau I, Welsch U, et al. First report of ectopic ACTH syndrome and PTHrP-induced hypercalcemia due to a hepatoblastoma in a child. Eur J Endocrinol. 2010;162:813–818.
Hsiao JC, Yang CP, Lin CJ, et al. Ectopic ACTH syndrome due to clear cell sarcoma of the kidney. Child Nephrol Urol. 1991;11:103–106.
Guran T, Turan S, Berrak SG, et al. Cushing’s syndrome due to a non-adrenal ectopic adrenocorticotropin-secreting Ewing’s sarcoma in a child. J Pediatr Endocrinol Metab. 2009;22:363–368.
Preeyasombat C, Sirikulchayanonta V, Mahachokelertwattana P, et al. Cushing’s syndrome caused by Ewing’s sarcoma sereting corticotropin releasing factor-like peptide. Am J Dis Child. 1992;146:1103–1105.

Auteurs

Abhinav K Tiwary (AK)

Baystate Medical Center.

Barbara Greco (B)

Baystate Medical Center.

Matthew W Richardson (MW)

University of Massachusetts Medical School-Baystate.
Baystate Children's Hospital, Springfield, MA.

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Classifications MeSH