Femur Neck Fracture in a Patient with Stiff Person Syndrome: A Case Report.


Journal

JBJS case connector
ISSN: 2160-3251
Titre abrégé: JBJS Case Connect
Pays: United States
ID NLM: 101596828

Informations de publication

Date de publication:
Historique:
pubmed: 26 7 2019
medline: 23 6 2020
entrez: 26 7 2019
Statut: ppublish

Résumé

A 57-year-old man with a known case of stiff person syndrome (SPS) presented with an insidious-onset 3-month history of right groin pain and inability to bear weight on the right lower extremity. Radiographs demonstrated a displaced right neck of femur fracture. Pelvic magnetic resonance imaging was negative for any infective or neoplastic pathology. Right primary cementless total hip replacement was performed. Significant improvement in function was noted after surgery. Femur neck fracture can result from severe muscle spasms and stiffness. Primary total hip replacement is a difficult but reasonable operative procedure for SPS with neck of femur fracture. The success of the procedure also depends on ideal medical control of muscle spasms and rigidity.

Identifiants

pubmed: 31343996
doi: 10.2106/JBJS.CC.18.00049
pii: 01709767-201909000-00011
doi:

Substances chimiques

Immunoglobulins, Intravenous 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0049

Références

Jachiet V, Laine L, Gendre T, Henry C, Da Silva D, de Montmollin E. Acute respiratory failure in a patient with stiff-person syndrome. Neurocrit Care. 2016;25(3):455-7.
T Chang, B Lang, A Vincent. Stiff person syndrome in South Asia. BMC Res Notes. 2016 9:468.
Levy LM, Dalaks MC, Floeter MK. The stiff-person syndrome: an autoimmune disorder affecting neurotransmission of gamma-aminobutyric acid. Ann Intern Med. 1999;131(7):522-30.
Bhatti A, Gazali Z. Recent advances and review on treatment of stiff person syndrome in adults and pediatric patients. Cureus. 2015;7(12):e427.
Pretorius E, Struwig W. Stiff person syndrome (SPS): literature review and case report. S Afr J Psych. 2013;19(4):228-31.
Henningsen P, Meinck HM. Specific phobia is a frequent non-motor feature in stiff man syndrome. J Neurol Neurosurg Psychiatry. 2003;74:462-5.
Dinkel K, Meinck HM, Jury KM, Karges W, Richter W. Inhibition of gamma-aminobutyric acid synthesis by glutamic acid decarboxylase autoantibodies in stiff-man syndrome. Ann Neurol. 1998;44(2):194-201.
Baizabal-Carvallo JF, Jankovic J. Stiff-person syndrome: insights into a complex autoimmune disorder. J Neurol Neurosurg Psychiatry. 2015;86(8):840-8.
Harding AE, Thompson PD, Kocen RS, Batchelor JR, Davey N, Marsden CD. Plasma exchange and immunosuppression in the stiff man syndrome. Lancet. 1989;2(8668):915.

Auteurs

Mujahid Jamil (M)

Section of Orthopedics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Muhammad Saleem (M)

Section of Orthopedics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Ahmed Habib (A)

Section of Orthopedics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

Sara Khan (S)

Section of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Muhammad Qahir (M)

Section of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.

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Classifications MeSH