Mesenchymal stem cells and IL-37: a powerful combination.

Cytokines Humans Inflammation Interleukin-1 / physiology Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells / cytology
IL-37 inflammation mesenchymal stem cells

Journal

Journal of biological regulators and homeostatic agents
ISSN: 0393-974X
Titre abrégé: J Biol Regul Homeost Agents
Pays: Italy
ID NLM: 8809253

Informations de publication

Date de publication:
Historique:
entrez: 27 7 2019
pubmed: 28 7 2019
medline: 1 8 2019
Statut: ppublish

Résumé

Mesenchymal stem cells (MSCs) are able to exert immunomodulatory and anti-inflammatory actions. Thanks to these properties, MSCs may be a promising alternative approach for the treatment of inflammatory disease. Important cytokines involved in inflammation are those included in the IL-1 family. Interleukin-37 (IL-37) is one of the member able to suppress both innate and adaptive immunity. Recently, it was found that MSCs and their derivatives can modulate IL-37, and MSCs expressing IL-37 seem to have an enhanced therapeutic efficacy.

Identifiants

PMID: 31347346
pubmed: 31347346
pii: 48

Substances chimiques

Cytokines 0
IL37 protein, human 0
Interleukin-1 0

Types de publication

Editorial

Langues

eng

Sous-ensembles de citation

IM

Pagination

1019-1022

Informations de copyright

Copyright 2019 Biolife Sas. www.biolifesas.org.

Auteurs

A Gugliandolo (A)

IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.

A L Caraffa (AL)

School of Pharmacy, University of Camerino, Camerino, Italy.

C E Gallenga (CE)

Department of Biomedical Sciences and Specialist Surgery, Section of Ophthalmology, University of Ferrara, Ferrara, Italy.

S K Kritas (SK)

Department of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, Macedonia, Greece.

G Ronconi (G)

Clinica dei Pazienti del Territorio, Fondazione Policlinico Gemelli, Rome, Italy.

O Trubiani (O)

Department of Oral and Biotechnology Medical Science, University of Chieti-Pescara, Chieti, Italy.

P Conti (P)

Postgraduate Medical School, University of Chieti, Chieti, Italy.

P Di Emidio (P)

Maxillofacial Surgery "G. Mazzini" Hospital, Teramo, Italy.

E Mazzon (E)

IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Mesenchymal stem cells and IL-37: a powerful...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Mesenchymal stem cells and IL-37: a powerful...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Mesenchymal stem cells and IL-37: a powerful...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Monokines › Interleukine-1 › Mesenchymal stem cells and IL-37: a powerful...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation cellulaire › Transplantation de cellules souches › Transplantation de cellules souches mésenchymateuses › Mesenchymal stem cells and IL-37: a powerful...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches multipotentes › Cellules souches mésenchymateuses › Mesenchymal stem cells and IL-37: a powerful...