The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines.
FGF21
IL-6
adiponectin
exercise
keto-adaptation
ketogenic diet
low-carbohydrate high-fat diet
microbiome
skeletal muscle
Journal
The American journal of clinical nutrition
ISSN: 1938-3207
Titre abrégé: Am J Clin Nutr
Pays: United States
ID NLM: 0376027
Informations de publication
Date de publication:
01 09 2019
01 09 2019
Historique:
received:
09
01
2019
accepted:
19
06
2019
pubmed:
28
7
2019
medline:
25
3
2020
entrez:
27
7
2019
Statut:
ppublish
Résumé
The ketogenic diet (KD) is a normocaloric diet composed of high-fat, low-carbohydrate, and adequate protein that induces fasting-like effects and results in the production of ketone bodies. Initially used widely for children with refractory epilepsy, the KD gained popularity due to its beneficial effects on weight loss, diabetes, and cancer. In recent years, there has been a resurgence in interest surrounding the KD and exercise performance. This review provides new insights into the adaptation period necessary for enhancement in skeletal muscle fat and ketone oxidation after sustained nutritional ketosis. In addition, this review highlights metabolically active growth factors and cytokines, which may function as important regulators of keto-adaptation in the setting of exercise and the KD.
Identifiants
pubmed: 31347659
pii: S0002-9165(22)01221-7
doi: 10.1093/ajcn/nqz145
doi:
Substances chimiques
Cytokines
0
Dietary Fats
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
562-573Informations de copyright
Copyright © American Society for Nutrition 2019.