Echo is a good, not perfect, measure of cardiac output in critically ill surgical patients.


Journal

The journal of trauma and acute care surgery
ISSN: 2163-0763
Titre abrégé: J Trauma Acute Care Surg
Pays: United States
ID NLM: 101570622

Informations de publication

Date de publication:
08 2019
Historique:
entrez: 27 7 2019
pubmed: 28 7 2019
medline: 23 1 2020
Statut: ppublish

Résumé

Compared with a pulmonary artery catheter (PAC), transthoracic echocardiography (TTE) has been shown to have good agreement in cardiac output (CO) measurement in nonsurgical populations. Our hypothesis is that the feasibility and accuracy of CO measured by TTE (CO-TTE), relative to CO measured by PAC thermodilution (CO-PAC), is different in surgical intensive care unit patients (SP) and nonsurgical patients (NSP). Surgical patients with PAC for hemodynamic monitoring and NSP undergoing right heart catheterization were prospectively enrolled. Cardiac output was measured by CO-PAC and CO-TTE. Pearson coefficients were used to assess correlation. Bland-Altman analysis was used to determine agreement. Over 18 months, 84 patients were enrolled (51 SP, 33 NSP). Cardiac output TTE could be measured in 65% (33/51) of SP versus 79% (26/33) of NSP; p = 0.17. Inability to measure the left ventricular outflow tract diameter was the primary reason for failure in both groups; 94% (17/18) in SP versus 86% (6/7) NSP; p = 0.47. Velocity time integral could be measured in all patients. In both groups, correlation between PAC and TTE measurement was strong; SP (r = 0.76; p < 0.0001), NSP (r = 0.86; p < 0.0001). Bland-Altman analysis demonstrated bias of -0.1 L/min, limits of agreement of -2.5 and +2.3 L/min, percentage error (PE) of 40% for SP, and bias of +0.4 L/min, limits of agreement of -1.8 and +2.5 L/min, and PE of 40% for NSP. There was strong correlation and moderate agreement between TTE and PAC in both SP and NSP. In both patient populations, inability to measure the left ventricular outflow tract diameter was a limiting factor. Diagnostic tests or criteria, level III.

Sections du résumé

BACKGROUND
Compared with a pulmonary artery catheter (PAC), transthoracic echocardiography (TTE) has been shown to have good agreement in cardiac output (CO) measurement in nonsurgical populations. Our hypothesis is that the feasibility and accuracy of CO measured by TTE (CO-TTE), relative to CO measured by PAC thermodilution (CO-PAC), is different in surgical intensive care unit patients (SP) and nonsurgical patients (NSP).
METHODS
Surgical patients with PAC for hemodynamic monitoring and NSP undergoing right heart catheterization were prospectively enrolled. Cardiac output was measured by CO-PAC and CO-TTE. Pearson coefficients were used to assess correlation. Bland-Altman analysis was used to determine agreement.
RESULTS
Over 18 months, 84 patients were enrolled (51 SP, 33 NSP). Cardiac output TTE could be measured in 65% (33/51) of SP versus 79% (26/33) of NSP; p = 0.17. Inability to measure the left ventricular outflow tract diameter was the primary reason for failure in both groups; 94% (17/18) in SP versus 86% (6/7) NSP; p = 0.47. Velocity time integral could be measured in all patients. In both groups, correlation between PAC and TTE measurement was strong; SP (r = 0.76; p < 0.0001), NSP (r = 0.86; p < 0.0001). Bland-Altman analysis demonstrated bias of -0.1 L/min, limits of agreement of -2.5 and +2.3 L/min, percentage error (PE) of 40% for SP, and bias of +0.4 L/min, limits of agreement of -1.8 and +2.5 L/min, and PE of 40% for NSP.
CONCLUSION
There was strong correlation and moderate agreement between TTE and PAC in both SP and NSP. In both patient populations, inability to measure the left ventricular outflow tract diameter was a limiting factor.
LEVEL OF EVIDENCE
Diagnostic tests or criteria, level III.

Identifiants

pubmed: 31349350
doi: 10.1097/TA.0000000000002304
pii: 01586154-201908000-00016
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

379-385

Auteurs

Peter P Olivieri (PP)

From the Subdepartment of Critical Care (P.P.O.), University of Maryland Baltimore Washington Medical Center, Glen Burnie; School of Medicine, Department of Anesthesiology (R.P.), University of Maryland; University of Maryland School of Medicine (S.K.); Division of Trauma and Surgical Critical Care, Department of Surgery, (S.F., T.M.S., S.B.M.), Department of Anesthesiology (S.M.G.), R Adams Cowley Shock Trauma Center, R Adams Cowley Shock Trauma Center, Department of Emergency Medicine, Division of Trauma and Critical Care, (D.J.H.), Division of Cardiovascular Medicine (G.V.R., H.A.), University of Maryland School of Medicine, Baltimore, Maryland; Division of Pulmonary and Critical Care (J.L.), Stanford University Medical Center, Stanford, California; Program in Shock Trauma, Department of Medicine (D.H.), and Division of Transplant Surgery (D.A.B.), University of Maryland School of Medicine, Baltimore, Maryland.

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