Endoscopic features of gastrointestinal stromal tumor in the small intestine.
Balloon-assisted enteroscopy
Dilated vessel
Gastrointestinal stromal tumors
Intestine, small
Journal
Intestinal research
ISSN: 1598-9100
Titre abrégé: Intest Res
Pays: Korea (South)
ID NLM: 101572802
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
12
12
2018
accepted:
19
04
2019
entrez:
30
7
2019
pubmed:
30
7
2019
medline:
30
7
2019
Statut:
ppublish
Résumé
Gastrointestinal stromal tumor (GIST) is one of the most common types of submucosal tumors (SMTs). Because of GIST's malignant potential, it is crucial to differentiate it from other SMTs. The present study aimed to identify characteristic endoscopic findings of GISTs in the small intestine. We reviewed the clinicopathological and endoscopic findings of 38 patients with endoscopically or surgically resected SMTs in the small intestine. SMTs were classified into GIST and non-GIST groups, and clinicopathological and endoscopic findings were compared between the 2 groups. Fifteen patients had GIST and 23 patients had other types of SMTs in the small intestine. Comparison of the endoscopic findings between the 2 groups revealed that dilated vessels in the surrounding mucosa were significantly more in number in the GIST group than in the non-GIST group (P<0.05). However, there were no other differences in endoscopic findings between the 2 groups. Among patients with GISTs, the presence of dilated vessels in the surrounding mucosa was not associated with bleeding risk, tumor size, or metastasis rate at diagnosis. Dilated vessels in the surrounding mucosa, identified during balloon-assisted endoscopy, may be a diagnostic indicator for GIST in the small intestine. However, its clinical significance should be further analyzed.
Sections du résumé
BACKGROUND/AIMS
OBJECTIVE
Gastrointestinal stromal tumor (GIST) is one of the most common types of submucosal tumors (SMTs). Because of GIST's malignant potential, it is crucial to differentiate it from other SMTs. The present study aimed to identify characteristic endoscopic findings of GISTs in the small intestine.
METHODS
METHODS
We reviewed the clinicopathological and endoscopic findings of 38 patients with endoscopically or surgically resected SMTs in the small intestine. SMTs were classified into GIST and non-GIST groups, and clinicopathological and endoscopic findings were compared between the 2 groups.
RESULTS
RESULTS
Fifteen patients had GIST and 23 patients had other types of SMTs in the small intestine. Comparison of the endoscopic findings between the 2 groups revealed that dilated vessels in the surrounding mucosa were significantly more in number in the GIST group than in the non-GIST group (P<0.05). However, there were no other differences in endoscopic findings between the 2 groups. Among patients with GISTs, the presence of dilated vessels in the surrounding mucosa was not associated with bleeding risk, tumor size, or metastasis rate at diagnosis.
CONCLUSIONS
CONCLUSIONS
Dilated vessels in the surrounding mucosa, identified during balloon-assisted endoscopy, may be a diagnostic indicator for GIST in the small intestine. However, its clinical significance should be further analyzed.
Identifiants
pubmed: 31352775
pii: ir.2018.00161
doi: 10.5217/ir.2018.00161
pmc: PMC6667370
doi:
Types de publication
Journal Article
Langues
eng
Pagination
398-403Références
Ann Surg Oncol. 2000 Oct;7(9):705-12
pubmed: 11034250
Gastrointest Endosc. 2001 Feb;53(2):216-20
pubmed: 11174299
Gastrointest Endosc. 2004 Jun;59(7):920-3
pubmed: 15173816
Dig Dis Sci. 2004 Apr;49(4):667-71
pubmed: 15185876
Am J Gastroenterol. 2005 Jan;100(1):162-8
pubmed: 15654796
J Gastroenterol. 2005 Mar;40(3):247-55
pubmed: 15830283
Arch Pathol Lab Med. 2006 Oct;130(10):1466-78
pubmed: 17090188
Semin Diagn Pathol. 2006 May;23(2):70-83
pubmed: 17193820
Cancer. 2008 Feb 1;112(3):608-15
pubmed: 18076015
Gastrointest Endosc. 2009 Sep;70(3):498-504
pubmed: 19555947
Gastrointest Endosc. 2011 Feb;73(2):227-37
pubmed: 21295636
Intern Med. 2012;51(19):2675-82
pubmed: 23037455
Gastroenterol Res Pract. 2012;2012:139083
pubmed: 23056038
Dig Endosc. 2015 Jan;27(1):44-52
pubmed: 25059428
J Surg Oncol. 2017 Mar;115(3):351-357
pubmed: 27885685
Digestion. 2017;95(2):122-131
pubmed: 28161705