Factors associated with stillbirth in women with diabetes.


Journal

Diabetologia
ISSN: 1432-0428
Titre abrégé: Diabetologia
Pays: Germany
ID NLM: 0006777

Informations de publication

Date de publication:
10 2019
Historique:
received: 16 01 2019
accepted: 20 05 2019
pubmed: 30 7 2019
medline: 2 6 2020
entrez: 30 7 2019
Statut: ppublish

Résumé

Stillbirth risk is increased in pregnancy complicated by diabetes. Fear of stillbirth has major influence on obstetric management, particularly timing of delivery. We analysed population-level data from Scotland to describe timing of stillbirths in women with diabetes and associated risk factors. A retrospective cohort of singleton deliveries to mothers with type 1 (n = 3778) and type 2 diabetes (n = 1614) from 1 April 1998 to 30 June 2016 was analysed using linked routine care datasets. Maternal and fetal characteristics, HbA Stillbirth rates were 16.1 (95% CI 12.4, 20.8) and 22.9 (95% CI 16.4, 31.8) per 1000 births in women with type 1 (n = 61) and type 2 diabetes (n = 37), respectively. In women with type 1 diabetes, higher HbA Maternal blood glucose levels and BMI are important modifiable risk factors for stillbirth in diabetes. Babies at extremes of weight centiles are at most risk. Many stillbirths occur at term and could potentially be prevented by change in routine care and delivery policies.

Identifiants

pubmed: 31353418
doi: 10.1007/s00125-019-4943-9
pii: 10.1007/s00125-019-4943-9
pmc: PMC6731193
doi:

Substances chimiques

Blood Glucose 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1938-1947

Subventions

Organisme : Chief Scientist Office
Pays : United Kingdom

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Auteurs

Sharon T Mackin (ST)

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

Scott M Nelson (SM)

School of Medicine, University of Glasgow, Glasgow, UK.

Sarah H Wild (SH)

Usher Institute of Population Health Science and Informatics, University of Edinburgh, Edinburgh, UK.

Helen M Colhoun (HM)

Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

Rachael Wood (R)

ISD Scotland, Edinburgh, UK.

Robert S Lindsay (RS)

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK. Robert.lindsay@glasgow.ac.uk.

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