Functional Characterization of Rare Variants in the

Shox2 arrhythmias atrial fibrillation cardiac conduction system pacemaker sinus node dysfunction transcription factor

Journal

Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621

Informations de publication

Date de publication:
2019
Historique:
received: 04 04 2019
accepted: 19 06 2019
entrez: 30 7 2019
pubmed: 30 7 2019
medline: 30 7 2019
Statut: epublish

Résumé

Sinus node dysfunction (SND) and atrial fibrillation (AF) often coexist; however, the molecular mechanisms linking both conditions remain elusive. Mutations in the homeobox-containing

Identifiants

pubmed: 31354791
doi: 10.3389/fgene.2019.00648
pmc: PMC6637028
doi:

Types de publication

Journal Article

Langues

eng

Pagination

648

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Auteurs

Sandra Hoffmann (S)

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Heidelberg/Mannheim, Heidelberg, Germany.

Christoph Paone (C)

Department of Internal Medicine II, University of Ulm, Ulm, Germany.

Simon A Sumer (SA)

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Heidelberg/Mannheim, Heidelberg, Germany.

Sabrina Diebold (S)

Department of Internal Medicine II, University of Ulm, Ulm, Germany.

Birgit Weiss (B)

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.

Ralph Roeth (R)

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.

Sebastian Clauss (S)

Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Munich, Munich, Germany.

Ina Klier (I)

Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Munich, Munich, Germany.

Stefan Kääb (S)

Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Munich, Munich, Germany.

Andreas Schulz (A)

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

Philipp S Wild (PS)

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

Adil Ghrib (A)

Department of General and Interventional Cardiology, University Heart Center Hamburg (UHZ), University Hospital Hamburg/Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Hamburg/Kiel/Luebeck, Hamburg, Germany.

Tanja Zeller (T)

Department of General and Interventional Cardiology, University Heart Center Hamburg (UHZ), University Hospital Hamburg/Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Hamburg/Kiel/Luebeck, Hamburg, Germany.

Renate B Schnabel (RB)

Department of General and Interventional Cardiology, University Heart Center Hamburg (UHZ), University Hospital Hamburg/Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Hamburg/Kiel/Luebeck, Hamburg, Germany.

Steffen Just (S)

Department of Internal Medicine II, University of Ulm, Ulm, Germany.

Gudrun A Rappold (GA)

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner site Heidelberg/Mannheim, Heidelberg, Germany.

Classifications MeSH