Diagnostic value of whole-body-focused ultrasonography in high-acuity patients in the emergency department: a prospective single-center cross-sectional study.


Journal

The ultrasound journal
ISSN: 2524-8987
Titre abrégé: Ultrasound J
Pays: Italy
ID NLM: 101742146

Informations de publication

Date de publication:
27 May 2019
Historique:
received: 01 11 2018
accepted: 20 05 2019
entrez: 31 7 2019
pubmed: 31 7 2019
medline: 31 7 2019
Statut: epublish

Résumé

A fast and diagnostic accurate tool to assess the unselected category of high-acuity patients, in whom the underlying pathology is not always obvious, is needed in the emergency departments (ED). We aim to describe the feasibility, validity and diagnostic yield of a routine whole-body-focused ultrasonography (wbf-us) in an unselected group of high-acuity ED patients. In a prospective observational study, a convenience sample of ED patients (≥ 18 years) with a high-acuity score or systolic blood pressure < 100 mmHg received a routine wbf-us of the heart, lungs, abdomen and deep veins by two non-expert sonographers. Final diagnosis was established by experienced auditors. Investigators were blinded to the patients' medical history and emergency physicians and auditors were blinded to the investigators assessments. Diagnostic accuracy was assessed by comparing the investigators' ultrasonography findings to a structured double-blinded clinical audit of patient files. We included 171 patients, initiated a whole-body-focused ultrasonography examination (wbf-us) in 160 and completed it in 128 patients with an average time of a full examination of 28 min. We found pathology in 65/171 (38%) of the patients whose most frequent symptoms upon arrival were cardiopulmonary. Among the patients who received wbf-us, we found the majority of pathology by wbf-us of the lungs (n = 50, 31%), the heart (n = 26, 16%), few in the abdomen (n = 5, 3%) and none in the deep veins. The overall sensitivity was 50-100%, specificity 84-94%, positive predictive value 11-44% and negative predictive value 94-100%. Focused cardiopulmonary ultrasonography might be considered for routine use in high-acuity ED patients with cardiopulmonary symptoms whereas focused ultrasonography of the abdomen and deep veins performed by non-expert sonographers only seems indicated in selected patients. Trial registration Danish Data Protection Agency (ID 13/12076). Committee on Biomedical Research Ethics for the Region of Southern Denmark (ID S-20130047).

Sections du résumé

BACKGROUND BACKGROUND
A fast and diagnostic accurate tool to assess the unselected category of high-acuity patients, in whom the underlying pathology is not always obvious, is needed in the emergency departments (ED). We aim to describe the feasibility, validity and diagnostic yield of a routine whole-body-focused ultrasonography (wbf-us) in an unselected group of high-acuity ED patients.
METHODS METHODS
In a prospective observational study, a convenience sample of ED patients (≥ 18 years) with a high-acuity score or systolic blood pressure < 100 mmHg received a routine wbf-us of the heart, lungs, abdomen and deep veins by two non-expert sonographers. Final diagnosis was established by experienced auditors. Investigators were blinded to the patients' medical history and emergency physicians and auditors were blinded to the investigators assessments. Diagnostic accuracy was assessed by comparing the investigators' ultrasonography findings to a structured double-blinded clinical audit of patient files.
RESULTS RESULTS
We included 171 patients, initiated a whole-body-focused ultrasonography examination (wbf-us) in 160 and completed it in 128 patients with an average time of a full examination of 28 min. We found pathology in 65/171 (38%) of the patients whose most frequent symptoms upon arrival were cardiopulmonary. Among the patients who received wbf-us, we found the majority of pathology by wbf-us of the lungs (n = 50, 31%), the heart (n = 26, 16%), few in the abdomen (n = 5, 3%) and none in the deep veins. The overall sensitivity was 50-100%, specificity 84-94%, positive predictive value 11-44% and negative predictive value 94-100%.
CONCLUSION CONCLUSIONS
Focused cardiopulmonary ultrasonography might be considered for routine use in high-acuity ED patients with cardiopulmonary symptoms whereas focused ultrasonography of the abdomen and deep veins performed by non-expert sonographers only seems indicated in selected patients. Trial registration Danish Data Protection Agency (ID 13/12076). Committee on Biomedical Research Ethics for the Region of Southern Denmark (ID S-20130047).

Identifiants

pubmed: 31359192
doi: 10.1186/s13089-019-0126-7
pii: 10.1186/s13089-019-0126-7
pmc: PMC6638611
doi:

Types de publication

Journal Article

Langues

eng

Pagination

11

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Auteurs

M Riishede (M)

The Research Section, Department of Surgery (A), Odense University Hospital, Baagoes Allé 15, 5700, Svendborg, Denmark. Minna.Riishede@rsyd.dk.
Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark. Minna.Riishede@rsyd.dk.
Department of Internal Medicine & Emergency Medicine (M/FAM), Odense University Hospital, Svendborg, Denmark. Minna.Riishede@rsyd.dk.

C B Laursen (CB)

Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark.
Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark.

L S Teglbjærg (LS)

Department of Internal Medicine & Emergency Medicine (M/FAM), Odense University Hospital, Svendborg, Denmark.

E Rancinger (E)

The Research Section, Department of Surgery (A), Odense University Hospital, Baagoes Allé 15, 5700, Svendborg, Denmark.

P B Pedersen (PB)

Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark.
Department of Internal Medicine & Emergency Medicine (M/FAM), Odense University Hospital, Svendborg, Denmark.

S M Luef (SM)

Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark.

J H Clausen (JH)

Department of Cardiology, Hospital of Southern Jutland, Aabenraa, Denmark.

O Graumann (O)

Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark.
Department of Radiology, Odense University Hospital, Odense, Denmark.

A T Lassen (AT)

Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark.
Department of Emergency Medicine, Odense University Hospital, Odense, Denmark.

G Baatrup (G)

The Research Section, Department of Surgery (A), Odense University Hospital, Baagoes Allé 15, 5700, Svendborg, Denmark.
Department of Clinical Research, University of Southern Denmark, SDU, Odense, Denmark.

Classifications MeSH