Current practices in the delivery of pharmacogenomics: Impact of the recommendations of the Pharmacy Practice Model Summit.


Journal

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
ISSN: 1535-2900
Titre abrégé: Am J Health Syst Pharm
Pays: England
ID NLM: 9503023

Informations de publication

Date de publication:
08 Apr 2019
Historique:
entrez: 31 7 2019
pubmed: 31 7 2019
medline: 21 1 2020
Statut: ppublish

Résumé

This report examines and evaluates pharmacogenomics as an emerging science as it relates to the Practice Advancement Initiative and its predecessor the Pharmacy Practice Model Initiative's consensus statements for optimal pharmacy practice models. Pharmacogenomics is one of many emerging sciences to impact medication management and delivery of patient care. Increasingly, biomarkers are included in drug labeling and can assist pharmacists with personalizing medicine to optimize patient therapies and avoid adverse effects. The 2011 ASHP Pharmacy Practice Model Summit generated a list of 147 consensus statements for optimal pharmacy practice. Of these, 1 statement explicitly describes adjustment of drug regimens based on genetic factors as an essential activity of pharmacist-provided drug regimens, and 9 other statements provide additional support for incorporation of this emerging science into all aspects of patient care provided by pharmacists. We describe 4 institutions that have made significant inroads to implementing pharmacogenomics, to provide a framework and serve as resources for other institutions initiating their own pharmacogenomics implementation journeys. Through prioritized efforts of the pharmacy profession and health care institutions, pharmacogenomics will be disseminated and implemented, and the goal of the Pharmacy Practice Model Initiative's consensus statements of improving health care using patients' genetic characteristics will be realized.

Identifiants

pubmed: 31361863
pii: 5427359
doi: 10.1093/ajhp/zxz024
pmc: PMC6480071
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

521-529

Subventions

Organisme : NHGRI NIH HHS
ID : U01 HG007269
Pays : United States

Informations de copyright

© American Society of Health-System Pharmacists 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Références

Med Law. 2008 Dec;27(4):843-57
pubmed: 19202860
Pharmacogenomics. 2010 Jan;11(1):13-21
pubmed: 20017668
N Engl J Med. 2011 Mar 24;364(12):1144-53
pubmed: 21428770
Am J Health Syst Pharm. 2011 Jun 15;68(12):1148-52
pubmed: 21642580
Am J Pharm Educ. 2011 Apr 11;75(3):51
pubmed: 21655405
J Clin Oncol. 2011 Aug 20;29(24):3232-9
pubmed: 21768473
Clin Pharmacol Ther. 2013 Aug;94(2):204-6
pubmed: 23588321
Genet Med. 2013 Oct;15(10):833-41
pubmed: 24009000
Pharmacogenomics. 2013 Oct;14(13):1593-603
pubmed: 24088130
Mayo Clin Proc. 2014 Jan;89(1):25-33
pubmed: 24388019
Am J Med Genet C Semin Med Genet. 2014 Mar;166C(1):56-67
pubmed: 24616371
Pharmacogenomics. 2014 May;15(7):915-23
pubmed: 24956245
Annu Rev Pharmacol Toxicol. 2015;55:89-106
pubmed: 25292429
Am J Pharm Educ. 2016 Sep 25;80(7):122
pubmed: 27756930
Am J Health Syst Pharm. 2016 Dec 1;73(23):1944-1954
pubmed: 27864202
Am J Health Syst Pharm. 2016 Dec 1;73(23):1956-1966
pubmed: 27864203
Am J Health Syst Pharm. 2016 Dec 1;73(23):1967-1976
pubmed: 27864204

Auteurs

John Valgus (J)

Hematology/Oncology Pharmacy Services, University of North Carolina Healthcare, and UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC.

Kristin W Weitzel (KW)

UF Health Personalized Medicine Program, University of Florida, and Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL.

Josh F Peterson (JF)

Vanderbilt University Medical Center, Nashville, TN.

Daniel J Crona (DJ)

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC.

Christine M Formea (CM)

Mayo Clinic College of Medicine, Hospital Pharmacy Services, Mayo Clinic, Rochester, MN.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH