Human chorionic gonadotropin and IL-35 contribute to the maintenance of peripheral immune tolerance during pregnancy through mediating the generation of IL-10
Abortion, Spontaneous
/ blood
Adult
Animals
B-Lymphocytes, Regulatory
/ drug effects
Case-Control Studies
Cell Proliferation
/ drug effects
Cells, Cultured
Chorionic Gonadotropin
/ blood
Disease Models, Animal
Female
Humans
Immune Tolerance
/ drug effects
Interleukin-10
/ metabolism
Interleukins
/ blood
Male
Mice
Mice, Inbred BALB C
Mice, Inbred CBA
Mice, Inbred DBA
Pregnancy
Pregnancy Maintenance
/ drug effects
Pregnancy Trimester, First
/ blood
Young Adult
B10 cells
Human chorionic gonadotropin
IL-35 producing regulatory B cells
Interleukin-35
Spontaneous abortion
Journal
Experimental cell research
ISSN: 1090-2422
Titre abrégé: Exp Cell Res
Pays: United States
ID NLM: 0373226
Informations de publication
Date de publication:
15 10 2019
15 10 2019
Historique:
received:
12
03
2019
revised:
25
07
2019
accepted:
26
07
2019
pubmed:
31
7
2019
medline:
1
7
2020
entrez:
31
7
2019
Statut:
ppublish
Résumé
Regulatory B cells (Breg cells) play critical roles in modulating immune responses during autoimmune diseases and infection. Here we explored the participation of two main Breg subsets, including IL-10
Identifiants
pubmed: 31362000
pii: S0014-4827(19)30356-8
doi: 10.1016/j.yexcr.2019.111513
pii:
doi:
Substances chimiques
Chorionic Gonadotropin
0
IL10 protein, human
0
Interleukins
0
interleukin-35, human
0
Interleukin-10
130068-27-8
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
111513Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.