Real-Time Detection of Spatial Disorientation in Persons with Mild Cognitive Impairment and Dementia.


Journal

Gerontology
ISSN: 1423-0003
Titre abrégé: Gerontology
Pays: Switzerland
ID NLM: 7601655

Informations de publication

Date de publication:
2020
Historique:
received: 26 08 2018
accepted: 15 05 2019
pubmed: 31 7 2019
medline: 4 8 2020
entrez: 31 7 2019
Statut: ppublish

Résumé

Detecting manifestations of spatial disorientation in real time is a key requirement for adaptive assistive navigation systems for people with dementia. To identify predictive patterns of spatial disorientation in cognitively impaired people during unconstrained locomotion behavior in an urban environment. Accelerometric data and GPS records were gathered during a wayfinding task along a route of about 1 km in 15 people with amnestic mild cognitive impairment or clinically probable Alzheimer's disease dementia (13 completers). We calculated a set of 48 statistical features for each 10-s segment of the acceleration sensor signal to characterize the physical motion. We used different classifiers with the wrapper method and leave-one-out cross-validation for feature selection and for determining accuracy of disorientation detection. Linear discriminant analysis using three features showed the best classification results, with a cross-validated ROC AUC of 0.75, detecting 65% of all scenes of spatial disorientation in real time. Consideration of an additional feature that informed about a person's distance to the next traffic junction did not provide an additional information gain. Accelerometric data are able to capture the uniformity and activity of a person's walking, which are identified as the most informative locomotion features of spatially disoriented behavior. This serves as an important basis for real-time navigation assistance. To improve the required accuracy of real-time disorientation prediction, as a next step we will analyze whether location-based behavior is able to inform about person-centered habitual factors of orientation.

Sections du résumé

BACKGROUND
Detecting manifestations of spatial disorientation in real time is a key requirement for adaptive assistive navigation systems for people with dementia.
OBJECTIVE
To identify predictive patterns of spatial disorientation in cognitively impaired people during unconstrained locomotion behavior in an urban environment.
METHODS
Accelerometric data and GPS records were gathered during a wayfinding task along a route of about 1 km in 15 people with amnestic mild cognitive impairment or clinically probable Alzheimer's disease dementia (13 completers). We calculated a set of 48 statistical features for each 10-s segment of the acceleration sensor signal to characterize the physical motion. We used different classifiers with the wrapper method and leave-one-out cross-validation for feature selection and for determining accuracy of disorientation detection.
RESULTS
Linear discriminant analysis using three features showed the best classification results, with a cross-validated ROC AUC of 0.75, detecting 65% of all scenes of spatial disorientation in real time. Consideration of an additional feature that informed about a person's distance to the next traffic junction did not provide an additional information gain.
CONCLUSIONS
Accelerometric data are able to capture the uniformity and activity of a person's walking, which are identified as the most informative locomotion features of spatially disoriented behavior. This serves as an important basis for real-time navigation assistance. To improve the required accuracy of real-time disorientation prediction, as a next step we will analyze whether location-based behavior is able to inform about person-centered habitual factors of orientation.

Identifiants

pubmed: 31362286
pii: 000500971
doi: 10.1159/000500971
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

85-94

Informations de copyright

© 2019 S. Karger AG, Basel.

Auteurs

Samer Schaat (S)

German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany, s.schaat@mailbox.org.

Philipp Koldrack (P)

German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.

Kristina Yordanova (K)

Department of Computer Science, University of Rostock, Rostock, Germany.

Thomas Kirste (T)

Department of Computer Science, University of Rostock, Rostock, Germany.

Stefan Teipel (S)

German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Department of Psychosomatic and Psychotherapeutic Medicine, University of Rostock, Rostock, Germany.

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